Rabbit polyclonal GALC antibody (A3873)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit polyclonal GALC antibody (A3873)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:100

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal GALC antibody.

Alternative names:

Check alternative names for the antibody

Expand

Gacy antibody|Galactocerebrosidase antibody|Galactocerebroside beta galactosidase antibody|Galactosylceramide beta galactosidase antibody|galactosylceraminidase antibody|Galc antibody|GALCERase antibody|Twitcher antibody|Anti-Galactosylceramidase antibody (ab137750)

SCBT cat No: sc-293200|sc-49287|sc-67352|sc-49289|

Name

Rabbit polyclonal GALC antibody

Catalogue No.

A3873

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human GALC

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 77kDa/Observed: Refer to figures

Formulation

GALC antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

GALC antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Database links

Human UniProt/Swiss-Prot:P54803

Protein function

Hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Enzyme with very low activity responsible for the lysosomal catabolism of galactosylceramide, a major lipid in myelin, kidney and epithelial cells of small intestine and colon.

Protein tissue specificity

Detected in urine. Detected in testis, brain and placenta (at protein level). Detected in kidney and liver.

Protein sequence and domain

Belongs to the glycosyl hydrolase 59 family.

Protein cellular localization

Lysosome.

Background

This gene encodes a lysosomal protein which hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Mutations in this gene have been associated with Krabbe disease, also known as globoid cell leukodystrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Note

AntibodyPlus can customize GALC antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!