Rabbit polyclonal GALNT2 antibody (A6910)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal GALNT2 antibody (A6910)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:100

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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GalNAc-T2 antibody
GalNAc T2 antibody|GalNAc-T2 antibody|Galnt2 antibody|GALT2_HUMAN antibody|GaNTase 2 antibody|Polypeptide GalNAc transferase 2 antibody|Polypeptide N acetylgalactosaminyltransferase 2 antibody|Polypeptide N acetylgalactosaminyltransferase 2 soluble form antibody|Polypeptide N-acetylgalactosaminyltransferase 2 soluble form antibody|pp GaNTase 2 antibody|pp-GaNTase 2 antibody|Protein UDP acetylgalactosaminyltransferase 2 antibody|Protein-UDP acetylgalactosaminyltransferase 2 antibody|UDP GalNAc transferase 2 antibody|UDP N acetyl alpha D galactosamine:polypeptide N acetylgalactosaminyltransferase 2 (GalNAc T2) antibody|UDP N acetyl alpha D galactosamine:polypeptide N acetylgalactosaminyltransferase 2 antibody|UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 2 antibody|Anti-GALNT2 antibody (ab102650)

SCBT cat No: sc-68511|

Name

Rabbit polyclonal GALNT2 antibody

Catalogue No.

A6910

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human GALNT2

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 65kDa/Observed: Refer to figures

Formulation

GALNT2 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

GALNT2 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

GalNAc-T2 antibody

Database links

Human UniProt/Swiss-Prot:Q10471

Protein names

GalNAc-T2

Protein function

Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b. Probably involved in O-linked glycosylation of the immunoglobulin A1 (IgA1) hinge region.

Protein tissue specificity

Widely expressed.

Protein sequence and domain

There are two conserved domains in the glycosyltransferase region: the N-terminal domain (domain A, also called GT1 motif), which is probably involved in manganese coordination and substrate binding and the C-terminal domain (domain B, also called Gal/GalNAc-T motif), which is probably involved in catalytic reaction and UDP-Gal binding.; The ricin B-type lectin domain binds to GalNAc and contributes to the glycopeptide specificity.Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.; Contains 1 ricin B-type lectin domain.

Protein cellular localization

Golgi apparatus, Golgi stack membrane ; Single-pass type II membrane protein . Secreted . Note: Resides preferentially in the trans and medial parts of the Golgi stack. A secreted form also exists.

Background

This gene encodes a member of the glycosyltransferase 2 protein family. Members of this family initiate mucin-type O-glycoslation of peptides in the Golgi apparatus. The encoded protein may be involved in O-linked glycosylation of the immunoglobulin A1 hinge region. This gene may influence triglyceride levels, and may be involved Type 2 diabetes, as well as several types of cancer. Alternative splicing results in multiple transcript variants.

Note

AntibodyPlus can customize GALNT2 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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