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Rabbit polyclonal GALNT2 antibody (A6910)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC,IF
WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:100
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal GALNT2 antibody.
Check alternative names for the antibodyExpand
GalNAc T2 antibody|GalNAc-T2 antibody|Galnt2 antibody|GALT2_HUMAN antibody|GaNTase 2 antibody|Polypeptide GalNAc transferase 2 antibody|Polypeptide N acetylgalactosaminyltransferase 2 antibody|Polypeptide N acetylgalactosaminyltransferase 2 soluble form antibody|Polypeptide N-acetylgalactosaminyltransferase 2 soluble form antibody|pp GaNTase 2 antibody|pp-GaNTase 2 antibody|Protein UDP acetylgalactosaminyltransferase 2 antibody|Protein-UDP acetylgalactosaminyltransferase 2 antibody|UDP GalNAc transferase 2 antibody|UDP N acetyl alpha D galactosamine:polypeptide N acetylgalactosaminyltransferase 2 (GalNAc T2) antibody|UDP N acetyl alpha D galactosamine:polypeptide N acetylgalactosaminyltransferase 2 antibody|UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 2 antibody|Anti-GALNT2 antibody (ab102650)
SCBT cat No: sc-68511|
Rabbit polyclonal GALNT2 antibody
|Catalogue No.|| |
Human, Mouse, Rat
Recombinant protein of human GALNT2
WB, IHC, IF
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 65kDa/Observed: Refer to figures
GALNT2 antibody was tube-contained.
GALNT2 antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
|Database links|| |
|Protein names|| |
|Protein function|| |
Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b. Probably involved in O-linked glycosylation of the immunoglobulin A1 (IgA1) hinge region.
|Protein tissue specificity|| |
|Protein sequence and domain|| |
There are two conserved domains in the glycosyltransferase region: the N-terminal domain (domain A, also called GT1 motif), which is probably involved in manganese coordination and substrate binding and the C-terminal domain (domain B, also called Gal/GalNAc-T motif), which is probably involved in catalytic reaction and UDP-Gal binding.; The ricin B-type lectin domain binds to GalNAc and contributes to the glycopeptide specificity.Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.; Contains 1 ricin B-type lectin domain.
|Protein cellular localization|| |
Golgi apparatus, Golgi stack membrane ; Single-pass type II membrane protein . Secreted . Note: Resides preferentially in the trans and medial parts of the Golgi stack. A secreted form also exists.
This gene encodes a member of the glycosyltransferase 2 protein family. Members of this family initiate mucin-type O-glycoslation of peptides in the Golgi apparatus. The encoded protein may be involved in O-linked glycosylation of the immunoglobulin A1 hinge region. This gene may influence triglyceride levels, and may be involved Type 2 diabetes, as well as several types of cancer. Alternative splicing results in multiple transcript variants.
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|Product type|| |
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