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Rabbit polyclonal GAP43 antibody (A6376)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC
WB 1:500 – 1:2000 IHC 1:50 – 1:200
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal GAP43 antibody.
Check alternative names for the antibodyExpand
B-50 antibody, PP46 antibody
Axonal membrane protein GAP 43 antibody|NEUM_HUMAN antibody|Neural phosphoprotein B 50 antibody|Neural phosphoprotein B-50 antibody|Neuromodulin antibody|Neuron growth associated protein 43 antibody|PP46 antibody|Protein F1 antibody|QtrA-11580 antibody|QtrA-13071 antibody|Anti-GAP43 antibody [EP890Y] (ab75810)
SCBT cat No: sc-135915|sc-33705|sc-17790|sc-7457|sc-10786|sc-7458|sc-47724|sc-59540|
Rabbit polyclonal GAP43 antibody
|Catalogue No.|| |
Human, Mouse, Rat
Recombinant protein of human GAP43
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 24kDa/Observed: Refer to figures
GAP43 antibody was tube-contained.
GAP43 antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
B-50 antibody, PP46 antibody
|Database links|| |
|Protein names|| |
|Protein function|| |
This protein is associated with nerve growth. It is a major component of the motile “growth cones” that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction.
|Protein sequence and domain|| |
Belongs to the neuromodulin family.; Contains 1 IQ domain.
|Protein post-translational modifications|| |
Phosphorylated at Ser-41 by PHK. Phosphorylation of this protein by a protein kinase C is specifically correlated with certain forms of synaptic plasticity.; Palmitoylation by ARF6 is essential for plasma membrane association and axonal and dendritic filopodia induction. Deacylated by LYPLA2.
|Protein cellular localization|| |
Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell projection, growth cone membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell junction, synapse . Cell projection, filopodium membrane ; Peripheral membrane protein . Note: Cytoplasmic surface of growth cone and synaptic plasma membranes.
The protein encoded by this gene has been termed a ‘growth’ or ‘plasticity’ protein because it is expressed at high levels in neuronal growth cones during development and axonal regeneration. This protein is considered a crucial component of an effective regenerative response in the nervous system. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
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|Product type|| |
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