Rabbit polyclonal GAP43 antibody (A6376)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal GAP43 antibody (A6376)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal GAP43 antibody.

Alternative names:

Check alternative names for the antibody

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B-50 antibody, PP46 antibody
Axonal membrane protein GAP 43 antibody|NEUM_HUMAN antibody|Neural phosphoprotein B 50 antibody|Neural phosphoprotein B-50 antibody|Neuromodulin antibody|Neuron growth associated protein 43 antibody|PP46 antibody|Protein F1 antibody|QtrA-11580 antibody|QtrA-13071 antibody|Anti-GAP43 antibody [EP890Y] (ab75810)

SCBT cat No: sc-135915|sc-33705|sc-17790|sc-7457|sc-10786|sc-7458|sc-47724|sc-59540|

Name

Rabbit polyclonal GAP43 antibody

Catalogue No.

A6376

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human GAP43

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 24kDa/Observed: Refer to figures

Formulation

GAP43 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

GAP43 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

B-50 antibody, PP46 antibody

Database links

Human UniProt/Swiss-Prot:P17677

Protein names

B-50, PP46

Protein function

This protein is associated with nerve growth. It is a major component of the motile “growth cones” that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction.

Protein sequence and domain

Belongs to the neuromodulin family.; Contains 1 IQ domain.

Protein post-translational modifications

Phosphorylated at Ser-41 by PHK. Phosphorylation of this protein by a protein kinase C is specifically correlated with certain forms of synaptic plasticity.; Palmitoylation by ARF6 is essential for plasma membrane association and axonal and dendritic filopodia induction. Deacylated by LYPLA2.

Protein cellular localization

Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell projection, growth cone membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell junction, synapse . Cell projection, filopodium membrane ; Peripheral membrane protein . Note: Cytoplasmic surface of growth cone and synaptic plasma membranes.

Background

The protein encoded by this gene has been termed a ‘growth’ or ‘plasticity’ protein because it is expressed at high levels in neuronal growth cones during development and axonal regeneration. This protein is considered a crucial component of an effective regenerative response in the nervous system. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Research area

All research areas>Neurobiology>GAP-43
(View all antibody categories related to Neurobiology)

Note

AntibodyPlus can customize GAP43 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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