Rabbit polyclonal GAS2 antibody (A1168)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal GAS2 antibody (A1168)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

GAS2 antibody,MGC32610 antibody
GAS 2 antibody|GAS-2 antibody|Gas2 antibody|GAS2_HUMAN antibody|Growth arrest specific 2 antibody|Growth arrest specific protein 2 antibody|Growth arrest-specific protein 2 antibody|MGC32610 antibody|Anti-GAS2 antibody (ab175290)

SCBT cat No: sc-54806|sc-398669|sc-101241|

Name

Rabbit polyclonal GAS2 antibody

Catalogue No.

A1168

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human GAS2

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 35kDa/Observed: Refer to Figures

Formulation

GAS2 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

GAS2 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

GAS2 antibody,MGC32610 antibody

Database links

Human UniProt/Swiss-Prot:O43903

Protein names

GAS2,MGC32610

Protein function

May play a role in apoptosis by acting as a cell death substrate for caspases. Is cleaved during apoptosis and the cleaved form induces dramatic rearrangements of the actin cytoskeleton and potent changes in the shape of the affected cells. May be involved in the membrane ruffling process (By similarity).

Protein tissue specificity

Ubiquitously expressed with highest levels in liver, lung, and kidney. Not found in spleen.

Protein sequence and domain

Belongs to the GAS2 family.; Contains 1 CH (calponin-homology) domain.; Contains 1 GAR domain.

Protein post-translational modifications

Cleaved, during apoptosis, on a specific aspartic residue by caspases.; Phosphorylated on serine residues during the G0-G1 transition phase.

Protein cellular localization

Cytoplasm, cytoskeleton . Membrane ; Peripheral membrane protein . Note: Component of the microfilament system. Colocalizes with actin fibers at the cell border and along the stress fibers in growth-arrested fibroblasts. Mainly membrane-associated. When hyperphosphorylated, accumulates at membrane ruffles (By similarity).

Background

The protein encoded by this gene is a caspase-3 substrate that plays a role in regulating microfilament and cell shape changes during apoptosis. It can also modulate cell susceptibility to p53-dependent apoptosis by inhibiting calpain activity. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2009]

Research area

All research areas>Tumor Suppressor/Apoptosis>Gas
(View all antibody categories related to Tumor Suppressor/Apoptosis)

Note

AntibodyPlus can customize GAS2 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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