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Rabbit polyclonal GAS2 antibody (A1168)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC,IF
WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal GAS2 antibody.
Check alternative names for the antibodyExpand
GAS2 antibody,MGC32610 antibody
GAS 2 antibody|GAS-2 antibody|Gas2 antibody|GAS2_HUMAN antibody|Growth arrest specific 2 antibody|Growth arrest specific protein 2 antibody|Growth arrest-specific protein 2 antibody|MGC32610 antibody|Anti-GAS2 antibody (ab175290)
SCBT cat No: sc-54806|sc-398669|sc-101241|
Rabbit polyclonal GAS2 antibody
|Catalogue No.|| |
Human, Mouse, Rat
Recombinant protein of human GAS2
WB, IHC, IF
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 35kDa/Observed: Refer to Figures
GAS2 antibody was tube-contained.
GAS2 antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
GAS2 antibody,MGC32610 antibody
|Database links|| |
|Protein names|| |
|Protein function|| |
May play a role in apoptosis by acting as a cell death substrate for caspases. Is cleaved during apoptosis and the cleaved form induces dramatic rearrangements of the actin cytoskeleton and potent changes in the shape of the affected cells. May be involved in the membrane ruffling process (By similarity).
|Protein tissue specificity|| |
Ubiquitously expressed with highest levels in liver, lung, and kidney. Not found in spleen.
|Protein sequence and domain|| |
Belongs to the GAS2 family.; Contains 1 CH (calponin-homology) domain.; Contains 1 GAR domain.
|Protein post-translational modifications|| |
Cleaved, during apoptosis, on a specific aspartic residue by caspases.; Phosphorylated on serine residues during the G0-G1 transition phase.
|Protein cellular localization|| |
Cytoplasm, cytoskeleton . Membrane ; Peripheral membrane protein . Note: Component of the microfilament system. Colocalizes with actin fibers at the cell border and along the stress fibers in growth-arrested fibroblasts. Mainly membrane-associated. When hyperphosphorylated, accumulates at membrane ruffles (By similarity).
The protein encoded by this gene is a caspase-3 substrate that plays a role in regulating microfilament and cell shape changes during apoptosis. It can also modulate cell susceptibility to p53-dependent apoptosis by inhibiting calpain activity. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2009]
AntibodyPlus can customize GAS2 antibody according to your requirement, including bulk product size,etc. Please contact email@example.com. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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