Rabbit polyclonal GATM antibody (A6598)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal GATM antibody (A6598)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

AT antibody, AGAT antibody, CCDS3 antibody
AGAT antibody|AT antibody|GATM antibody|GATM_HUMAN antibody|Glycine amidinotransferase antibody|Glycine amidinotransferase, mitochondrial antibody|L-arginine:glycine amidinotransferase antibody|mitochondrial antibody|Transamidinase antibody|Anti-GATM antibody (ab87062)

SCBT cat No: sc-241785|

Name

Rabbit polyclonal GATM antibody

Catalogue No.

A6598

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human GATM

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 48kDa/Observed: Refer to figures

Formulation

GATM antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

GATM antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

AT antibody, AGAT antibody, CCDS3 antibody

Database links

Human UniProt/Swiss-Prot:P50440

Protein names

AT, AGAT, CCDS3

Protein function

Catalyzes the biosynthesis of guanidinoacetate, the immediate precursor of creatine. Creatine plays a vital role in energy metabolism in muscle tissues. May play a role in embryonic and central nervous system development. May be involved in the response to heart failure by elevating local creatine synthesis.

Protein tissue specificity

Expressed in brain, heart, kidney, liver, lung, salivary gland and skeletal muscle tissue, with the highest expression in kidney. Biallelically expressed in placenta and fetal tissues.

Protein sequence and domain

One chain folds into a compact single domain composed of repeating units, five beta-beta-alpha-beta modules, which surround the central active site.Belongs to the amidinotransferase family.

Protein cellular localization

Isoform 1: Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side. Note: Probably attached to the outer side of the inner membrane.; Isoform 2: Cytoplasm.

Background

This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by mental retardation, language impairment, and behavioral disorders.

Note

AntibodyPlus can customize GATM antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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