Rabbit polyclonal GBA3 antibody (A7827)

$69.00$259.00

Reactivity: Human,Mouse
Applications: WB,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal GBA3 antibody (A7827)

Supplier: ABclonal Inc.

Recommended applications: WB,IF

Recommended dilution:

WB 1:500 – 1:2000 IF 1:50 – 1:100

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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CBG antibody, GLUC antibody, KLRP antibody, CBGL1 antibody
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SCBT cat No:

Name

Rabbit polyclonal GBA3 antibody

Catalogue No.

A7827

Reactivity

Human, Mouse

Immunogen

Recombinant protein of human GBA3

Host

Rabbit

Applications

WB, IF

Recommended dilution

WB 1:500 – 1:2000
IF 1:50 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 54kDa/Observed: Refer to figures

Formulation

GBA3 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

GBA3 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

CBG antibody, GLUC antibody, KLRP antibody, CBGL1 antibody

Database links

Human UniProt/Swiss-Prot:Q9H227

Protein names

CBG, GLUC, KLRP, CBGL1

Protein function

Glycosidase probably involved in the intestinal absorption and metabolism of dietary flavonoid glycosides. Able to hydrolyze a broad variety of glycosides including phytoestrogens, flavonols, flavones, flavanones and cyanogens. Possesses beta-glycosylceramidase activity and may be involved in a nonlysosomal catabolic pathway of glycosylceramide.

Protein tissue specificity

Present in small intestine (at protein level). Expressed in liver, small intestine, colon, spleen and kidney. Down-regulated in renal cell carcinomas and hepatocellular carcinomas.

Protein sequence and domain

Belongs to the glycosyl hydrolase 1 family. Klotho subfamily.

Protein post-translational modifications

The N-terminus is blocked.

Protein cellular localization

Cytoplasm, cytosol .

Background

The protein encoded by this gene is an enzyme that can hydrolyze several types of glycosides. This gene is a polymorphic pseudogene, with the most common allele being the functional allele that encodes the full-length protein. Some individuals, as represented by the reference genome allele, contain a single nucleotide polymorphism that results in a premature stop codon in the coding region, and therefore this allele is pseudogenic due to the failure to produce a functional full-length protein. Alternative splicing of this gene results in multiple transcript variants.

Research area

All research areas>Synthesis and Degradation>CBG
(View all antibody categories related to Synthesis and Degradation)

Note

AntibodyPlus can customize GBA3 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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