Rabbit polyclonal GBP1 antibody (A6911)

$69.00$259.00

Reactivity: Human
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal GBP1 antibody (A6911)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:100

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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GBP 1 antibody|GBP-1 antibody|GBP1 antibody|GBP1_HUMAN antibody|GTP binding protein 1 antibody|GTP-binding protein 1 antibody|Guanine nucleotide binding protein 1 antibody|Guanine nucleotide-binding protein 1 antibody|Guanylate binding protein 1 antibody|Guanylate binding protein 1 interferon inducible 67kDa antibody|Guanylate binding protein 1 interferon inducible antibody|HuGBP 1 antibody|HuGBP-1 antibody|HuGBP1 antibody|Interferon induced guanylate binding protein 1 antibody|Interferon-induced guanylate-binding protein 1 antibody|OTTHUMP00000012352 antibody|Anti-GBP1 antibody [EPR8285] (ab131255)

SCBT cat No: sc-53857|sc-10586|sc-10579|sc-10584|

Name

Rabbit polyclonal GBP1 antibody

Catalogue No.

A6911

Reactivity

Human

Immunogen

Recombinant protein of human GBP1

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 68kDa/Observed: Refer to figures

Formulation

GBP1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

GBP1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Database links

Human UniProt/Swiss-Prot:P32455

Protein function

Hydrolyzes GTP to GMP in 2 consecutive cleavage reactions. Exhibits antiviral activity against influenza virus. Promote oxidative killing and deliver antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes.

Protein sequence and domain

Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3-type GTPase family. GB1 subfamily.; Contains 1 GB1/RHD3-type G (guanine nucleotide-binding) domain.

Protein post-translational modifications

Isoprenylation is required for proper subcellular location.

Protein cellular localization

Cytoplasm . Golgi apparatus membrane; Lipid-anchor ; Cytoplasmic side. Cell membrane . Secreted. Note: Secreted from endothelial cells in the cerebrospinal fluid, upon bacterial challenge and independently of IFNG induction. Golgi membrane localization requires isoprenylation and the presence of another IFNG-induced factor.

Background

Guanylate binding protein expression is induced by interferon. Guanylate binding proteins are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP) and are distinguished from the GTP-binding proteins by the presence of 2 binding motifs rather than 3.

Research area

All research areas>GDP/GTP Binding Proteins>GBP
(View all antibody categories related to GDP/GTP Binding Proteins)

Note

AntibodyPlus can customize GBP1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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