Rabbit polyclonal GC antibody (A5709)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal GC antibody (A5709)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:10 – 1:100

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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DBP antibody, GRD3 antibody, VDBG antibody, VDBP antibody, DBP/GC antibody, HEL-S-51 antibody
DBP antibody|DBP/GC antibody|GC antibody|Gc globulin antibody|Gc-globulin antibody|GRD3 antibody|Group specific component antibody|Group specific component vitamin D binding protein antibody|Group-specific component antibody|hDBP antibody|VDB antibody|VDBG antibody|VDBP antibody|Vitamin D binding alpha globulin antibody|Vitamin D-binding protein antibody|VTDB_HUMAN antibody|Anti-HSV1 ICP8 Major DNA binding protein antibody [11E2] (ab20194)

SCBT cat No:

Name

Rabbit polyclonal GC antibody

Catalogue No.

A5709

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human GC

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:10 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 52kDa/Observed: Refer to Figures

Formulation

GC antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

GC antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

DBP antibody, GRD3 antibody, VDBG antibody, VDBP antibody, DBP/GC antibody, HEL-S-51 antibody

Database links

Human UniProt/Swiss-Prot:P02774

Protein names

DBP, GRD3, VDBG, VDBP, DBP/GC, HEL-S-51

Protein function

Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation.

Protein tissue specificity

Expressed in the liver. Found in plasma, ascites, cerebrospinal fluid and urine.

Protein sequence and domain

Belongs to the ALB/AFP/VDB family.; Contains 3 albumin domains.

Protein post-translational modifications

Allele GC*1S is O-glycosylated at Thr-436 . The trisaccharide sugar moiety can be modified by the successive removal of neuraminic acid and galactose leaving an O-linked N-acetyl-galactosamine. This conversion is thought to produce a macrophage-activating factor (Gc-MAF). Only a minor proportion of plasma GC is O-glycosylated . The potential N-glycosylation site predicted at Asn-288 is thought to be nonglycosylated.

Protein cellular localization

Secreted.

Background

The protein encoded by this gene belongs to the albumin gene family. It is a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid and on the surface of many cell types. It binds to vitamin D and its plasma metabolites and transports them to target tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Research area

All research areas>Transport and Trafficking>DBP
(View all antibody categories related to Transport and Trafficking)

Note

AntibodyPlus can customize GC antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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