Rabbit polyclonal GDAP1 antibody (A6601)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal GDAP1 antibody (A6601)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

CMT4 antibody, CMT4A antibody, CMTRIA antibody
Charcot Marie Tooth neuropathy 4A antibody|CMT4 antibody|CMT4A antibody|CMTRIA antibody|Ganglioside induced differentiation associated protein 1 antibody|Ganglioside-induced differentiation-associated protein 1 antibody|GDAP1 antibody|GDAP1_HUMAN antibody|Anti-GDAP1 antibody (ab100905)

SCBT cat No: sc-86468|sc-98516|

Name

Rabbit polyclonal GDAP1 antibody

Catalogue No.

A6601

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human GDAP1

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 41kDa/Observed: Refer to figures

Formulation

GDAP1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

GDAP1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

CMT4 antibody, CMT4A antibody, CMTRIA antibody

Database links

Human UniProt/Swiss-Prot:Q8TB36

Protein names

CMT4, CMT4A, CMTRIA

Protein function

Regulates the mitochondrial network by promoting mitochondrial fission.

Protein tissue specificity

Highly expressed in whole brain and spinal cord. Predominant expression in central tissues of the nervous system not only in neurons but also in Schwann cells.

Protein sequence and domain

Belongs to the GST superfamily.; Contains 1 GST C-terminal domain.; Contains 1 GST N-terminal domain.

Protein post-translational modifications

Ubiquitinated by PARK2 during mitophagy, leading to its degradation and enhancement of mitophagy. Deubiquitinated by USP30.

Protein cellular localization

Mitochondrion outer membrane ; Multi-pass membrane protein . Cytoplasm .

Background

This gene encodes a member of the ganglioside-induced differentiation-associated protein family, which may play a role in a signal transduction pathway during neuronal development. Mutations in this gene have been associated with various forms of Charcot-Marie-Tooth Disease and neuropathy. Two transcript variants encoding different isoforms and a noncoding variant have been identified for this gene.

Note

AntibodyPlus can customize GDAP1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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