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Rabbit polyclonal GDF9 antibody (A2739)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC
WB 1:500 – 1:1000 IHC 1:50 – 1:100
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal GDF9 antibody.
Check alternative names for the antibodyExpand
SCBT cat No:
Rabbit polyclonal GDF9 antibody
|Catalogue No.|| |
Human, Mouse, Rat
Recombinant protein of human GDF9
|Recommended dilution|| |
WB 1:500 – 1:1000
|Molecular weight|| |
Predicted: 51kDa/Observed: Refer to Figures
GDF9 antibody was tube-contained.
GDF9 antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
|Database links|| |
|Protein names|| |
|Protein function|| |
Required for ovarian folliculogenesis. Promotes primordial follicle development. Stimulates granulosa cell proliferation. Promotes cell transition from G0/G1 to S and G2/M phases, through an increase of CCND1 and CCNE1 expression, and RB1 phosphorylation. It regulates STAR expression and cAMP-dependent progesterone release in granulosa and thecal cells. Attenuates the suppressive effects of activin A on STAR expression and progesterone production by increasing the expression of inhibin B. It suppresses FST and FSTL3 production in granulosa-lutein cells.
|Protein tissue specificity|| |
Expressed in ovarian granulosa cells. Present in oocytes of primary follicles (at protein level).
|Protein sequence and domain|| |
Belongs to the TGF-beta family.
|Protein post-translational modifications|| |
Phosphorylated; phosphorylation is critical for GDF9 function. In vitro, can be phosphorylated by CK at Ser-325.
|Protein cellular localization|| |
Growth factors synthesized by ovarian somatic cells directly affect oocyte growth and function. Growth differentiation factor-9 (GDF9) is expressed in oocytes and is thought to be required for ovarian folliculogenesis. GDF9 is a member of the transforming growth factor-beta superfamily.
AntibodyPlus can customize GDF9 antibody according to your requirement, including bulk product size,etc. Please contact firstname.lastname@example.org. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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