Rabbit polyclonal GLO1 antibody (A1932)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal GLO1 antibody (A1932)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

GLYI antibody, GLOD1 antibody
Aldoketomutase antibody|glo1 antibody|GLOD1 antibody|Glx I antibody|GLYI antibody|glyoxalase domain containing 1 antibody|Glyoxalase I antibody|Ketone aldehyde mutase antibody|Ketone-aldehyde mutase antibody|Lactoyl glutathione lyase antibody|Lactoylglutathione lyase antibody|LGUL_HUMAN antibody|Methylglyoxalase antibody|S D lactoylglutathione methylglyoxal lyase antibody|S-D-lactoylglutathione methylglyoxal lyase antibody|Anti-GLO1 antibody [6F10] (ab81461)

SCBT cat No: sc-101537|sc-133214|sc-133144|sc-67351|sc-133213|sc-101877|sc-271556|sc-50731|

Name

Rabbit polyclonal GLO1 antibody

Catalogue No.

A1932

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human GLO1

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 21kDa/Observed: Refer to Figures

Formulation

GLO1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

GLO1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

GLYI antibody, GLOD1 antibody

Database links

Human UniProt/Swiss-Prot:Q04760

Protein names

GLYI, GLOD1

Protein function

Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. Involved in the regulation of TNF-induced transcriptional activity of NF-kappa-B. Required for normal osteoclastogenesis.

Protein sequence and domain

Belongs to the glyoxalase I family.

Protein post-translational modifications

Glutathionylation at Cys-139 inhibits enzyme activity.; Phosphorylated at Thr-107 in the presence of CaMK2. However, this is a consensus site for phosphorylation by CK2 so phosphorylation may be mediated by CK2 rather than CaMK2. Phosphorylation is induced by TNF and suppresses the TNF-induced transcriptional activity of NF-kappa-B.; Exists in a nitric oxide (NO)-modified form. The exact nature of the modification is unknown, but it suppresses the TNF-induced transcriptional activity of NF-kappa-B.

Background

The enzyme encoded by this gene is responsible for the catalysis and formation of S-lactoyl-glutathione from methylglyoxal condensation and reduced glutatione. Glyoxalase I is linked to HLA and is localized to 6p21.3-p21.1, between HLA and the centromere.

Note

AntibodyPlus can customize GLO1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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