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Rabbit polyclonal GNA11 antibody (A2731)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC
WB 1:500 – 1:2000 IHC 1:50 – 1:200
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal GNA11 antibody.
Check alternative names for the antibodyExpand
G alpha-11 antibody|G-protein subunit alpha-11 antibody|GA11 antibody|GNA11 antibody|GNA11_HUMAN antibody|guanine nucleotide binding protein (G protein), alpha 11 (Gq class) antibody|Guanine nucleotide-binding protein G(y) subunit alpha antibody|Guanine nucleotide-binding protein subunit alpha-11 antibody|guanine nucleotide-binding protein, alpha 11 antibody|guanine nucleotide-binding protein, Gq class, GNA11 antibody|Anti-GNA11 antibody (ab153951)
SCBT cat No: sc-394|sc-390382|sc-26792|sc-28588|sc-515445|
Rabbit polyclonal GNA11 antibody
|Catalogue No.|| |
Human, Mouse, Rat
Recombinant protein of human GNA11
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 42kDa/Observed: Refer to Figures
GNA11 antibody was tube-contained.
GNA11 antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
|Database links|| |
|Protein names|| |
|Protein function|| |
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Acts as an activator of phospholipase C.
|Protein tissue specificity|| |
Expressed in testis.
|Protein sequence and domain|| |
Belongs to the G-alpha family. G(q) subfamily.
|Protein post-translational modifications|| |
(Microbial infection) Deamidated at Gln-209 by Photorhabdus asymbiotica toxin PAU_02230, blocking GTP hydrolysis of heterotrimeric GNAQ or GNA11 and G-alphai (GNAI1, GNAI2 or GNAI3) proteins, thereby activating RhoA.
|Protein cellular localization|| |
Cell membrane ; Lipid-anchor . Cytoplasm . Note: In testicular cells, expressed exclusively in the cytoplasm.
Heterotrimeric guanine nucleotide-binding proteins (G proteins) consist of alpha, beta and gamma subunits and mediate the effects of hormones, neurotransmitters, chemokines and sensory stimuli. To date, over 20 known Galpha subunits have been classified into four families, Galpha(s), Galpha(i/o), Galpha(q) and Galpha(12), based on structural and functional similarities (1,2). Phosphorylation of Tyr356 of Galpha(q)/Galpha(11) is essential for activation of the G protein, since phenylalanine substitution for Tyr356 changes the interaction of Galpha with receptors and abolishes ligand-induced IP3 formation (3).
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|Product type|| |
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