Rabbit polyclonal GNL3 antibody (A6459)

$69.00$259.00

Reactivity: Human
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal GNL3 antibody (A6459)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:10 – 1:100

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

NS antibody, E2IG3 antibody, NNP47 antibody, C77032 antibody
C77032 antibody|E2 induced gene 3 protein antibody|E2-induced gene 3 protein antibody|E2IG3 antibody|Estradiol induced nucleotide binding protein antibody|GNL3 antibody|GNL3_HUMAN antibody|Guanine nucleotide binding protein like 3 (nucleolar) antibody|Guanine nucleotide binding protein like 3 antibody|Guanine nucleotide-binding protein-like 3 antibody|MGC800 antibody|NNP47 antibody|Novel nucleolar protein 47 antibody|NS antibody|Nucleolar GTP binding protein 3 antibody|Nucleolar GTP-binding protein 3 antibody|Nucleostemin antibody|Putative nucleotide binding protein estradiol induced antibody|Anti-Nucleostemin antibody (ab70346)

SCBT cat No: sc-166430|sc-46212|sc-46215|sc-166460|sc-398978|sc-67012|sc-67013|sc-46219|

Name

Rabbit polyclonal GNL3 antibody

Catalogue No.

A6459

Reactivity

Human

Immunogen

Recombinant protein of human GNL3

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:10 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 61kDa/Observed: Refer to Figures

Formulation

GNL3 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

GNL3 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

NS antibody, E2IG3 antibody, NNP47 antibody, C77032 antibody

Database links

Human UniProt/Swiss-Prot:Q9BVP2

Protein names

NS, E2IG3, NNP47, C77032

Protein function

May be required to maintain the proliferative capacity of stem cells. Stabilizes MDM2 by preventing its ubiquitination, and hence proteasomal degradation (By similarity).

Protein tissue specificity

Increased levels in lung tissue in cancer patients.

Protein sequence and domain

The basic domain (B) allows nucleolar localization in the absence of GTP. The intermediate domain (I) inhibits nucleolar localization by the B domain and is required for exit from the nucleolus. Exit from the nucleolus to the nucleoplasm requires both the I and the acidic (A) domains, and may be triggered by GTP hydrolysis (By similarity).; In contrast to other GTP-binding proteins, this family is characterized by a circular permutation of the GTPase motifs described by a G4-G1-G3 pattern.Belongs to the TRAFAC class YlqF/YawG GTPase family.; Contains 1 CP-type G (guanine nucleotide-binding) domain.

Protein cellular localization

Nucleus . Nucleus, nucleolus . Note: Shuttles between the nucleus and nucleolus.

Background

The protein encoded by this gene may interact with p53 and may be involved in tumorigenesis. The encoded protein also appears to be important for stem cell proliferation. This protein is found in both the nucleus and nucleolus. Three transcript variants encoding two different isoforms have been found for this gene.

Note

AntibodyPlus can customize GNL3 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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