Rabbit polyclonal GORASP1 antibody (A6609)

$69.00$259.00

Reactivity: Human
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal GORASP1 antibody (A6609)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:10 – 1:100

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal GORASP1 antibody.

Alternative names:

Check alternative names for the antibody

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P65 antibody, GOLPH5 antibody, GRASP65 antibody
FLJ23443 antibody|Golgi peripheral membrane protein p65 antibody|Golgi phosphoprotein 5 antibody|Golgi reassembly and stacking protein 1 antibody|Golgi reassembly and stacking protein 65 kDa antibody|Golgi reassembly and stacking protein, 65-kD antibody|Golgi reassembly stacking protein 1 65kDa antibody|Golgi reassembly stacking protein 1 antibody|Golgi reassembly stacking protein of 65 kDa antibody|Golgi reassembly-stacking protein 1 antibody|Golgi reassembly-stacking protein of 65 kDa antibody|GOLPH 5 antibody|GOLPH5 antibody|Gorasp 1 antibody|GORASP1 antibody|GORS1_HUMAN antibody|GRASP 65 antibody|GRASP65 antibody|MGC118894 antibody|MGC118897 antibody|P65 antibody|Anti-GRASP65 antibody (ab30315)

SCBT cat No: sc-398363|sc-19481|sc-374423|sc-365412|sc-365434|sc-30093|

Name

Rabbit polyclonal GORASP1 antibody

Catalogue No.

A6609

Reactivity

Human

Immunogen

Recombinant protein of human GORASP1

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:10 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 46kDa/Observed: Refer to figures

Formulation

GORASP1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

GORASP1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

P65 antibody, GOLPH5 antibody, GRASP65 antibody

Database links

Human UniProt/Swiss-Prot:Q9BQQ3

Protein names

P65, GOLPH5, GRASP65

Protein function

Stacking factor involved in the postmitotic assembly of Golgi stacks from mitotic Golgi fragments. Key structural protein required for the maintenance of the Golgi apparatus integrity: its caspase-mediated cleavage is required for fragmentation of the Golgi during apoptosis (By similarity). Also mediates, via its interaction with GOLGA2/GM130, the docking of transport vesicles with the Golgi membranes .

Protein sequence and domain

Belongs to the GORASP family.; Contains 1 PDZ (DHR) domain.

Protein post-translational modifications

Phosphorylated by CDC2/B1 and PLK kinases during mitosis. Phosphorylation cycle correlates with the cisternal stacking cycle. Phosphorylation of the homodimer prevents the association of dimers into higher-order oligomers, leading to cisternal unstacking.; Target for caspase-3 cleavage during apoptosis. The cleavage contributes to Golgi fragmentation and occurs very early in the execution phase of apoptosis (By similarity).

Protein cellular localization

Golgi apparatus, cis-Golgi network membrane ; Peripheral membrane protein ; Cytoplasmic side . Note: Undergoes rapid exchange with the cytosol.

Background

The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is a membrane protein involved in establishing the stacked structure of the Golgi apparatus. It is a caspase-3 substrate, and cleavage of this encoded protein contributes to Golgi fragmentation in apoptosis. This encoded protein can form a complex with the Golgi matrix protein GOLGA2, and this complex binds to the vesicle docking protein p115. Alternative splicing results in multiple transcript variants of this gene.

Research area

All research areas>Transport and Trafficking>GRASP
(View all antibody categories related to Transport and Trafficking)

Note

AntibodyPlus can customize GORASP1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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