Rabbit polyclonal GOT1 antibody (A5822)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal GOT1 antibody (A5822)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:10 – 1:100

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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cCAT antibody, GIG18 antibody, cAspAT antibody, ASTQTL1 antibody
AATC_HUMAN antibody|Aspartate aminotransferase 1 antibody|Aspartate aminotransferase antibody|Aspartate aminotransferase cytoplasmic antibody|Aspartate aminotransferase cytosolic antibody|ASTQTL1 antibody|cAspAT antibody|cCAT antibody|cysteine aminotransferase, cytoplasmic antibody|cysteine transaminase, cytoplasmic antibody|cytoplasmic antibody|ec 2.6.1.1 antibody|GIG 18 antibody|GIG18 antibody|Glutamate oxaloacetate transaminase 1 antibody|Glutamate oxaloacetate transaminase soluble antibody|Glutamic oxaloacetic transaminase 1 soluble antibody|GOT 1 antibody|GOT1 antibody|Growth inhibiting protein 18 antibody|SGOT antibody|Transaminase A antibody|Anti-Aspartate Aminotransferase antibody [EPR12145] (ab170950)

SCBT cat No: sc-46281|sc-367196|sc-46283|

Name

Rabbit polyclonal GOT1 antibody

Catalogue No.

A5822

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human GOT1

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:10 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 46kDa/Observed: Refer to Figures

Formulation

GOT1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

GOT1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

cCAT antibody, GIG18 antibody, cAspAT antibody, ASTQTL1 antibody

Database links

Human UniProt/Swiss-Prot:P17174

Protein names

cCAT, GIG18, cAspAT, ASTQTL1

Protein function

Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-mercaptopyruvate sulfurtransferase (3MST). Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain.

Protein sequence and domain

Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

Protein cellular localization

Cytoplasm .

Background

Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology.

Note

AntibodyPlus can customize GOT1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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