Rabbit polyclonal GPHN antibody (A8572)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal GPHN antibody (A8572)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:100

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal GPHN antibody.

Alternative names:

Check alternative names for the antibody

Expand

GPH antibody, GEPH antibody, HKPX1 antibody, GPHRYN antibody, MOCODC antibody
Domain E antibody|Domain G antibody|GEPH antibody|GEPH_HUMAN antibody|GPH antibody|GPHN antibody|GPHRYN antibody|KIAA1385 antibody|Molybdopterin molybdenumtransferase antibody|MPT adenylyltransferase antibody|MPT Mo-transferase antibody|Anti-Gephyrin antibody (ab32206)

SCBT cat No: sc-135920|sc-55469|sc-25311|sc-6411|sc-14003|

Name

Rabbit polyclonal GPHN antibody

Catalogue No.

A8572

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human GPHN

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 80kDa/Observed: Refer to figures

Formulation

GPHN antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

GPHN antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

GPH antibody, GEPH antibody, HKPX1 antibody, GPHRYN antibody, MOCODC antibody

Database links

Human UniProt/Swiss-Prot:Q9NQX3

Protein names

GPH, GEPH, HKPX1, GPHRYN, MOCODC

Protein function

Microtubule-associated protein involved in membrane protein-cytoskeleton interactions. It is thought to anchor the inhibitory glycine receptor (GLYR) to subsynaptic microtubules. Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.

Protein sequence and domain

In the N-terminal section; belongs to the MoaB/Mog family.; In the C-terminal section; belongs to the MoeA family.

Protein cellular localization

Cell junction, synapse . Cell junction, synapse, postsynaptic cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasm, cytoskeleton . Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell projection, dendrite . Note: Cytoplasmic face of glycinergic postsynaptic membranes.

Background

This gene encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described; however, the full-length nature of all transcript variants is not currently known.

Note

AntibodyPlus can customize GPHN antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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