Rabbit polyclonal GPI antibody (A6916)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal GPI antibody (A6916)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:100 IF 1:50 – 1:100

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal GPI antibody.

Alternative names:

Check alternative names for the antibody

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AMF antibody, NLK antibody, PGI antibody, PHI antibody, GNPI antibody, SA36 antibody, SA-36 antibody
AMF antibody|Aurocrine motility factor antibody|Autocrine motility factor antibody|DKFZp686C13233 antibody|EC 5.3.1.9 antibody|G6PI_HUMAN antibody|Glucose phosphate isomerase antibody|Glucose-6-phosphate isomerase antibody|GNPI antibody|GPI antibody|Gpi1 antibody|Hexose monophosphate isomerase antibody|Hexosephosphate isomerase antibody|Neuroleukin antibody|NLK antibody|Oxoisomerase antibody|PGI antibody|PHI antibody|Phosphoglucose isomerase antibody|Phosphohexomutase antibody|Phosphohexose isomerase antibody|Phosphosaccharomutase antibody|SA 36 antibody|SA-36 antibody|SA36 antibody|Sperm antigen 36 antibody|Anti-Glucose 6 phosphate isomerase antibody (ab86950)

SCBT cat No: sc-130067|sc-398381|sc-398382|sc-365066|sc-33777|sc-271459|sc-30392|

Name

Rabbit polyclonal GPI antibody

Catalogue No.

A6916

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human GPI

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:100
IF 1:50 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 63kDa/Observed: Refer to figures

Formulation

GPI antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

GPI antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

AMF antibody, NLK antibody, PGI antibody, PHI antibody, GNPI antibody, SA36 antibody, SA-36 antibody

Database links

Human UniProt/Swiss-Prot:P06744

Protein names

AMF, NLK, PGI, PHI, GNPI, SA36, SA-36

Protein function

Besides it’s role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons.

Protein sequence and domain

Belongs to the GPI family.

Protein post-translational modifications

Phosphorylation at Ser-185 by CK2 has been shown to decrease enzymatic activity and may contribute to secretion by a non-classical secretory pathway.; ISGylated.

Protein cellular localization

Cytoplasm . Secreted .

Background

This gene encodes a member of the glucose phosphate isomerase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In the cytoplasm, the gene product functions as a glycolytic enzyme (glucose-6-phosphate isomerase) that interconverts glucose-6-phophsate and fructose-6-phosphate. Extracellularly, the encoded protein (also referred to as neuroleukin) functions as a neurotrophic factor that promotes survival of skeletal motor neurons and sensory neurons, and as a lymphokine that induces immunoglobulin secretion. The encoded protein is also referred to as autocrine motility factor based on an additional function as a tumor-secreted cytokine and angiogenic factor. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment. Alternative splicing results in multiple transcript variants.

Research area

All research areas>Synthesis and Degradation>GPI
(View all antibody categories related to Synthesis and Degradation)

Note

AntibodyPlus can customize GPI antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

Reviews


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Antibody customer reviews & validation data - 187

Validation data ID: 187

Submission date: 2017-04-28

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Result figure:
Result figure

Figure description:

This antibody works well on my murine tissue extracts (from 2-week-old kidney, liver, and lung) and Cos 7 cell extract.

Product name

Rabbit poluclonal GPI antibody

Product catalog No.

A6916

Product type

Primary antibody

Supplier

ABclonal

Application type

Western Blot

Antibody specificity rating

Excellent

Antibody overall rating

Excellent

Your comments

This antibody works well on my murine tissue extracts (from 2-week-old kidney, liver, and lung) and Cos 7 cell extract.

Detailed protocol

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