Rabbit polyclonal GPX4 antibody (A1933)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal GPX4 antibody (A1933)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:10 – 1:100

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

MCSP antibody, GPx-4 antibody, PHGPx antibody, snGPx antibody, GSHPx-4 antibody, snPHGPx antibody
Glutathione peroxidase 4 antibody|GPX 4 antibody|GPX-4 antibody|GPX4 antibody|GPX4_HUMAN antibody|GSHPx-4 antibody|MCSP antibody|mitochondrial antibody|PHGPx antibody|Phospholipid hydroperoxidase antibody|Phospholipid hydroperoxide glutathione peroxidase antibody|Phospholipid hydroperoxide glutathione peroxidase mitochondrial antibody|snGPx antibody|snPHGPx antibody|Sperm nucleus glutathione peroxidase antibody|Anti-Glutathione Peroxidase 4 antibody [EPNCIR144] (ab125066)

SCBT cat No: sc-166120|sc-166437|sc-166570|sc-50497|sc-27529|

Name

Rabbit polyclonal GPX4 antibody

Catalogue No.

A1933

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human GPX4

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:10 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 22kDa/Observed: Refer to Figures

Formulation

GPX4 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

GPX4 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

MCSP antibody, GPx-4 antibody, PHGPx antibody, snGPx antibody, GSHPx-4 antibody, snPHGPx antibody

Database links

Human UniProt/Swiss-Prot:P36969

Protein names

MCSP, GPx-4, PHGPx, snGPx, GSHPx-4, snPHGPx

Protein function

Protects cells against membrane lipid peroxidation and cell death. Required for normal sperm development and male fertility. Could play a major role in protecting mammals from the toxicity of ingested lipid hydroperoxides. Essential for embryonic development. Protects from radiation and oxidative damage. Essential for maturation and survival of photoreceptor cells. Plays a role in a primary T cell response to viral and parasitic infection by protecting T cells from ferroptosis, a cell death resulting from an iron-dependent accumulation of lipid reactive oxygen species, and by supporting T cell expansion.

Protein tissue specificity

Present primarily in testis.

Protein sequence and domain

Belongs to the glutathione peroxidase family.

Protein cellular localization

Isoform Mitochondrial: Mitochondrion.; Isoform Cytoplasmic: Cytoplasm.

Background

Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, experimental evidence for alternative splicing exists; alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified. [provided by RefSeq, Jul 2008]

Note

AntibodyPlus can customize GPX4 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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