Rabbit polyclonal GRM8 antibody (A2964)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit polyclonal GRM8 antibody (A2964)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal GRM8 antibody.

Alternative names:

Check alternative names for the antibody

Expand

GLUR8 antibody, mGlu8 antibody, GPRC1H antibody, MGLUR8 antibody
FLJ41058 antibody|GLUR8 antibody|Glutamate receptor metabotropic 8 antibody|GPRC1H antibody|GRM8 antibody|GRM8_HUMAN antibody|Metabotropic glutamate receptor 8 antibody|MGC126724 antibody|mGlu8 antibody|mGluR8 antibody|Anti-Metabotropic Glutamate Receptor 8 antibody (ab176301)

SCBT cat No: sc-517124|sc-30300|sc-47158|

Name

Rabbit polyclonal GRM8 antibody

Catalogue No.

A2964

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide of human GRM8

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 102kDa/Observed: Refer to Figures

Formulation

GRM8 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

GRM8 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

GLUR8 antibody, mGlu8 antibody, GPRC1H antibody, MGLUR8 antibody

Database links

Human UniProt/Swiss-Prot:O00222

Protein names

GLUR8, mGlu8, GPRC1H, MGLUR8

Protein function

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.

Protein sequence and domain

Belongs to the G-protein coupled receptor 3 family.

Protein cellular localization

Cell membrane; Multi-pass membrane protein.

Background

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Research area

All research areas>Membrane Receptors>mGluR
(View all antibody categories related to Membrane Receptors)

Note

AntibodyPlus can customize GRM8 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!