Rabbit polyclonal GSN antibody (A2952)

$69.00$259.00

Reactivity: Human,Mouse
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal GSN antibody (A2952)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

ADF antibody, AGEL antibody
Actin depolymerizing factor antibody|Actin-depolymerizing factor antibody|ADF antibody|AGEL antibody|Brevin antibody|DKFZp313L0718 antibody|GELS_HUMAN antibody|Gelsolin antibody|Gsn antibody|Anti-Gelsolin antibody [GS-2C4] (ab11081)

SCBT cat No: sc-57509|sc-22602|sc-6405|sc-271001|sc-514502|sc-398244|sc-48769|sc-6406|sc-22600|

Name

Rabbit polyclonal GSN antibody

Catalogue No.

A2952

Reactivity

Human, Mouse

Immunogen

Recombinant protein of human GSN

Host

Rabbit

Applications

WB

Recommended dilution

WB 1:500 – 1:2000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 90kDa/Observed: Refer to Figures

Formulation

GSN antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

GSN antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

ADF antibody, AGEL antibody

Database links

Human UniProt/Swiss-Prot:P06396

Protein names

ADF, AGEL

Protein function

Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis.

Protein tissue specificity

Phagocytic cells, platelets, fibroblasts, nonmuscle cells, smooth and skeletal muscle cells.

Protein sequence and domain

Belongs to the villin/gelsolin family.; Contains 6 gelsolin-like repeats.

Protein post-translational modifications

Phosphorylation on Tyr-86, Tyr-409, Tyr-465, Tyr-603 and Tyr-651 in vitro is induced in presence of phospholipids.

Protein cellular localization

Isoform 2: Cytoplasm, cytoskeleton.; Isoform 1: Secreted.

Background

The protein encoded by this gene binds to the “plus” ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene.

Note

AntibodyPlus can customize GSN antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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