Rabbit polyclonal GTF2IRD1 antibody (A6613)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal GTF2IRD1 antibody (A6613)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal GTF2IRD1 antibody.

Alternative names:

Check alternative names for the antibody

Expand

BEN antibody, WBS antibody, GTF3 antibody, RBAP2 antibody, CREAM1 antibody, MUSTRD1 antibody, WBSCR11 antibody, WBSCR12 antibody, hMusTRD1alpha1 antibody
CREAM1 antibody|General transcription factor II I repeat domain containing protein 1 antibody|General transcription factor II-I repeat domain-containing protein 1 antibody|General transcription factor III antibody|GT2D1_HUMAN antibody|GTF2I repeat domain containing protein 1 antibody|GTF2I repeat domain-containing protein 1 antibody|GTF2IRD1 antibody|GTF3 antibody|Muscle TFII I repeat domain-containing protein 1 antibody|Muscle TFII-I repeat domain-containing protein 1 antibody|MUSTRD1 antibody|MusTRD1/BEN antibody|RBAP2 antibody|Slow muscle fiber enhancer binding protein antibody|Slow-muscle-fiber enhancer-binding protein antibody|USE B1 binding protein antibody|USE B1-binding protein antibody|WBSCR11 antibody|WBSCR12 antibody|Williams Beuren syndrome chromosome region 11 protein antibody|Williams-Beuren syndrome chromosomal region 11 protein antibody|Williams-Beuren syndrome chromosomal region 12 protein antibody|Anti-GTF2IRD1 antibody [GTF5I102] (ab51524)

SCBT cat No:

Name

Rabbit polyclonal GTF2IRD1 antibody

Catalogue No.

A6613

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human GTF2IRD1

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 106kDa/Observed: Refer to figures

Formulation

GTF2IRD1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

GTF2IRD1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

BEN antibody, WBS antibody, GTF3 antibody, RBAP2 antibody, CREAM1 antibody, MUSTRD1 antibody, WBSCR11 antibody, WBSCR12 antibody, hMusTRD1alpha1 antibody

Database links

Human UniProt/Swiss-Prot:Q9UHL9

Protein names

BEN, WBS, GTF3, RBAP2, CREAM1, MUSTRD1, WBSCR11, WBSCR12, hMusTRD1alpha1

Protein function

May be a transcription regulator involved in cell-cycle progression and skeletal muscle differentiation. May repress GTF2I transcriptional functions, by preventing its nuclear residency, or by inhibiting its transcriptional activation. May contribute to slow-twitch fiber type specificity during myogenesis and in regenerating muscles. Binds troponin I slow-muscle fiber enhancer (USE B1). Binds specifically and with high affinity to the EFG sequences derived from the early enhancer of HOXC8 (By similarity).

Protein tissue specificity

Highly expressed in adult skeletal muscle, heart, fibroblast, bone and fetal tissues. Expressed at lower levels in all other tissues tested.

Protein sequence and domain

The N-terminal half may have an activating activity.Belongs to the TFII-I family.; Contains 5 GTF2I-like repeats.

Protein cellular localization

Nucleus.

Background

The protein encoded by this gene contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix (HLH) motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive transcriptional regulator under the control of Retinoblastoma protein. This gene plays a role in craniofacial and cognitive development and mutations have been associated with Williams-Beuren syndrome, a multisystem developmental disorder caused by deletion of multiple genes at 7q11.23. Alternative splicing results in multiple transcript variants.

Research area

All research areas>Transcription Regulators>WBSCR
(View all antibody categories related to Transcription Regulators)

Note

AntibodyPlus can customize GTF2IRD1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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