Rabbit polyclonal GUCY2D antibody (A3605)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal GUCY2D antibody (A3605)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:200 – 1:2000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal GUCY2D antibody.

Alternative names:

Check alternative names for the antibody

Expand

LCA antibody, CYGD antibody, LCA1 antibody, RCD2 antibody, CORD5 antibody, CORD6 antibody, GUC2D antibody, ROSGC antibody, retGC antibody, GUC1A4 antibody, RETGC-1 antibody, ROS-GC1 antibody
CORD6 antibody|guanylate cyclase 2D membrane (retina-specific) antibody|GUC1A4 antibody|GUC2D antibody|LCA antibody|LCA1 antibody|retGC antibody|RETGC-1 antibody|ROS-GC1 antibody|Anti-PGCD antibody (ab55224)

SCBT cat No: sc-34520|sc-514879|sc-376217|sc-34521|sc-50512|

Name

Rabbit polyclonal GUCY2D antibody

Catalogue No.

A3605

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human GUCY2D

Host

Rabbit

Applications

WB

Recommended dilution

WB 1:200 – 1:2000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 120kDa/Observed: Refer to figures

Formulation

GUCY2D antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

GUCY2D antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

LCA antibody, CYGD antibody, LCA1 antibody, RCD2 antibody, CORD5 antibody, CORD6 antibody, GUC2D antibody, ROSGC antibody, retGC antibody, GUC1A4 antibody, RETGC-1 antibody, ROS-GC1 antibody

Database links

Human UniProt/Swiss-Prot:Q02846

Protein names

LCA, CYGD, LCA1, RCD2, CORD5, CORD6, GUC2D, ROSGC, retGC, GUC1A4, RETGC-1, ROS-GC1

Protein function

Probably plays a specific functional role in the rods and/or cones of photoreceptors. It may be the enzyme involved in the resynthesis of cGMP required for recovery of the dark state after phototransduction.

Protein tissue specificity

Retina. Localized exclusively in the nuclei and inner segments of the rod and cone photoreceptor cells.

Protein sequence and domain

Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.; Contains 1 guanylate cyclase domain.; Contains 1 protein kinase domain.

Protein cellular localization

Membrane; Single-pass type I membrane protein.

Background

This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases.

Note

AntibodyPlus can customize GUCY2D antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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