Rabbit polyclonal GYS1 antibody (A2519)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal GYS1 antibody (A2519)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:100

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

GSY antibody, GYS antibody
Glycogen [starch] synthase antibody|Glycogen synthase 1 (muscle) antibody|Glycogen synthase 1 antibody|GSY antibody|GYS antibody|Gys1 antibody|GYS1_HUMAN antibody|muscle antibody|Anti-Glycogen synthase 1 antibody [EP817Y] (ab40810)

SCBT cat No: sc-47188|

Name

Rabbit polyclonal GYS1 antibody

Catalogue No.

A2519

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human GYS1

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 84kDa/Observed: Refer to figures

Formulation

GYS1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

GYS1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

GSY antibody, GYS antibody

Database links

Human UniProt/Swiss-Prot:P13807

Protein names

GSY, GYS

Protein function

Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

Protein sequence and domain

Belongs to the glycosyltransferase 3 family.

Protein post-translational modifications

Phosphorylation at Ser-8 by AMPK inactivates the enzyme activity. Primed phosphorylation at Ser-657 (site 5) by CSNK2A1 and CSNK2A2 is required for inhibitory phosphorylation at Ser-641 (site 3a), Ser-645 (site 3b), Ser-649 (site 3c) and Ser-653 (site 4) by GSK3A an GSK3B (By similarity). Phosphorylated at Ser-641 by DYRK2, leading to inactivation (By similarity). Phosphorylated at Ser-641 by PASK, leading to inactivation; phosphorylation by PASK is inhibited by glycogen. Dephosphorylation at Ser-641 and Ser-645 by PP1 activates the enzyme.

Background

The protein encoded by this gene catalyzes the addition of glucose monomers to the growing glycogen molecule through the formation of alpha-1,4-glycoside linkages. Mutations in this gene are associated with muscle glycogen storage disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Research area

All research areas>Synthesis and Degradation>Glycogen Synthase
(View all antibody categories related to Synthesis and Degradation)

Note

AntibodyPlus can customize GYS1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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