Rabbit polyclonal GZMB antibody (A2557)

$69.00$259.00

Reactivity: Human,Mouse
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal GZMB antibody (A2557)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal GZMB antibody.

Alternative names:

Check alternative names for the antibody

Expand

HLP antibody, CCPI antibody, CGL1 antibody, CSPB antibody, SECT antibody, CGL-1 antibody, CSP-B antibody, CTLA1 antibody, CTSGL1 antibody
C11 antibody|Cathepsin G like 1 antibody|Cathepsin G-like 1 antibody|CCPI antibody|CGL 1 antibody|CGL1 antibody|CSP B antibody|CSPB antibody|CTLA-1 antibody|CTLA1 antibody|CTSGL1 antibody|Cytotoxic serine protease B antibody|Cytotoxic T lymphocyte associated serine esterase 1 antibody|Cytotoxic T lymphocyte proteinase 2 antibody|Cytotoxic T-lymphocyte proteinase 2 antibody|Fragmentin 2 antibody|Fragmentin-2 antibody|GRAB_HUMAN antibody|Granzyme 2 antibody|Granzyme B (granzyme 2, cytotoxic T lymphocyte associated serine esterase 1) antibody|Granzyme B antibody|Granzyme-2 antibody|GranzymeB antibody|GRB antibody|Gzmb antibody|Hlp antibody|Human lymphocyte protein antibody|Lymphocyte protease antibody|Protease, serine, B antibody|SECT antibody|T cell serine protease 1-3E antibody|T-cell serine protease 1-3E antibody|Anti-Granzyme B antibody (ab4059)

SCBT cat No: sc-8022|sc-1968|sc-56119|sc-73620|sc-133636|

Name

Rabbit polyclonal GZMB antibody

Catalogue No.

A2557

Reactivity

Human, Mouse

Immunogen

Recombinant protein of human GZMB

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 27kDa/Observed: Refer to Figures

Formulation

GZMB antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

GZMB antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

HLP antibody, CCPI antibody, CGL1 antibody, CSPB antibody, SECT antibody, CGL-1 antibody, CSP-B antibody, CTLA1 antibody, CTSGL1 antibody

Database links

Human UniProt/Swiss-Prot:P10144

Protein names

HLP, CCPI, CGL1, CSPB, SECT, CGL-1, CSP-B, CTLA1, CTSGL1

Protein function

This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.

Protein sequence and domain

Belongs to the peptidase S1 family. Granzyme subfamily.; Contains 1 peptidase S1 domain.

Protein cellular localization

Cytoplasmic granule . Note: Cytoplasmic granules of cytolytic T-lymphocytes and natural killer cells.

Background

Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface ‘nonself’ antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response.

Research area

All research areas>Tumor Suppressor/Apoptosis>Granzyme
(View all antibody categories related to Tumor Suppressor/Apoptosis)

Note

AntibodyPlus can customize GZMB antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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