Rabbit Polyclonal HABP2 antibody (STJ90086)

$99.00$319.00

Reactivity: Human, Mouse, Rat
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal HABP2 antibody (STJ90086)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-1:2000; ELISA 1:5000;

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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HABP2 antibody, HGFAL antibody, PHBP antibody,|Factor seven activating protease antibody|Factor seven-activating protease antibody|Factor VII activating protein antibody|Factor VII-activating protease antibody|FSAP antibody|HABP 2 antibody|HABP antibody|Habp2 antibody|HABP2_HUMAN antibody|Hepatocyte growth factor activator like protein antibody|Hepatocyte growth factor activator-like protein antibody|HGFAL antibody|Hyaluronan binding protein 2 antibody|Hyaluronan-binding protein 2 27 kDa light chain alternate form antibody|Hyaluronic acid binding protein 2 antibody|PHBP antibody|Plasma hyaluronan binding protein antibody|Plasma hyaluronan-binding protein antibody|Anti-HABP2 antibody [EPR14551] (ab181837)
SCBT cat No: sc-131540|sc-131547|

 

Name

HABP2 Polyclonal Antibody

Catalogue No.

STJ90086

Reactivity

Human, Mouse, Rat

Specificity

HABP2 Polyclonal Antibody detects endogenous levels of HABP2 protein.

Immunogen

Synthesized peptide derived from HABP2 at AA range 270-350

Host

Rabbit

Applications

WB, ELISA

Recommended dilution

WB 1:500-1:2000; ELISA 1:5000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

63 kDa

Formulation

HABP2 Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

HABP2 Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Hyaluronan-binding protein 2 antibody, Factor VII-activating protease antibody, Factor seven-activating protease antibody, FSAP antibody, Hepatocyte growth factor activator-like protein antibody, Plasma hyaluronan-binding protein antibody

Database links

Human UniProt/Swiss-Prot:Q14520;Mouse UniPort/Swiss-Prot: Q8K0D2;Rat UniProt/Swiss-Port: Q6L711;Human Entrez Gene: 3026;Mouse Entrez Gene: 226243;Rat Entrez Gene: Rn.161908

Protein names

Hyaluronan-binding protein 2 , Factor VII-activating protease , Factor seven-activating protease , FSAP , Hepatocyte growth factor activator-like protein , Plasma hyaluronan-binding protein

Protein function

Cleaves the alpha-chain at multiple sites and the beta-chain between ‘Lys-53’ and ‘Lys-54’ but not the gamma-chain of fibrinogen and therefore does not initiate the formation of the fibrin clot and does not cause the fibrinolysis directly. It does not cleave (activate) prothrombin and plasminogen but converts the inactive single chain urinary plasminogen activator (pro-urokinase) to the active two chain form. Activates coagulation factor VII . May function as a tumor suppressor negatively regulating cell proliferation and cell migration .

Protein tissue specificity

Ubiquitously expressed.

Involvement in disease

Thyroid cancer, non-medullary, 5 (NMTC5) [MIM:616535]: A form of non-medullary thyroid cancer (NMTC), a cancer characterized by tumors originating from the thyroid follicular cells. NMTCs represent approximately 95% of all cases of thyroid cancer and are classified into papillary, follicular, Hurthle cell, and anaplastic neoplasms. . Note: Disease susceptibility is associated with variations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the peptidase S1 family. / Contains 3 EGF-like domains. / Contains 1 kringle domain. / Contains 1 peptidase S1 domain.

Protein post-translational modifications

Proteolytic cleavage at Gly-23 or Met-27 can give rise to the 50 kDa heavy chain and cleavage at Arg-313 or Lys-319 can give rise to the 27 kDa light chain. The heavy chain can undergo further proteolytic cleavage at Lys-169 or Arg-170 to give rise to 2 inactive 26 kDa fragments and the light chain can undergo further proteolytic cleavage at Arg-480 to give rise to inactive 17 kDa and 8 kDa fragments (By similarity).

Protein cellular localization

Secreted

Research area

All research areas>Growth Factors and Hormones>HABP
(View all antibody categories related to Growth Factors and Hormones)

Note

AntibodyPlus can customize HABP2 Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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