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Rabbit polyclonal HAT1 antibody (A6188)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC,IF,IP,ChIP
WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200 IP 1:50 – 1:200 ChIP 1:20 – 1:100
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal HAT1 antibody.
Check alternative names for the antibodyExpand
HAT 1 antibody|hat1 antibody|HAT1_HUMAN antibody|Histidine aminotransferase 1 antibody|Histone acetyltransferase 1 antibody|Histone acetyltransferase 1 antibody|Histone acetyltransferase type B catalytic subunit antibody|KAT1 antibody|Anti-KAT1 / HAT1 antibody [EPR18775] (ab194296)
SCBT cat No: sc-376268|sc-8752|sc-376200|sc-366092|sc-390562|
Rabbit polyclonal HAT1 antibody
|Catalogue No.|| |
Human, Mouse, Rat
Recombinant protein of human HAT1
WB, IHC, IF, IP, ChIP
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 49kDa/Observed: Refer to Figures
HAT1 antibody was tube-contained.
HAT1 antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
|Database links|| |
|Protein names|| |
|Protein function|| |
Acetylates soluble but not nucleosomal histone H4 at ‘Lys-5’ (H4K5ac) and ‘Lys-12’ (H4K12ac) and, to a lesser extent, acetylates histone H2A at ‘Lys-5’ (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. May be involved in nucleosome assembly during DNA replication and repair as part of the histone H3.1 and H3.3 complexes. May play a role in DNA repair in response to free radical damage.
|Protein sequence and domain|| |
Belongs to the HAT1 family.
|Protein cellular localization|| |
Isoform A: Nucleus matrix.; Isoform B: Cytoplasm. Nucleus. Nucleus matrix. Nucleus, nucleoplasm. Note: Localization is predominantly nuclear in normal cells. Treatment with hydrogen peroxide or ionizing radiation enhances nuclear localization through redistribution of existing protein.
The protein encoded by this gene is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5. Alternatively spliced transcript variants have been identified for this gene.
AntibodyPlus can customize HAT1 antibody according to your requirement, including bulk product size,etc. Please contact email@example.com. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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