Rabbit polyclonal HAX1 antibody (A5551)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal HAX1 antibody (A5551)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:10 – 1:100

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal HAX1 antibody.

Alternative names:

Check alternative names for the antibody

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SCN3 antibody, HS1BP1 antibody, HCLSBP1 antibody
FLJ17042 antibody|FLJ18492 antibody|FLJ93803 antibody|HAX 1 antibody|HAX-1 antibody|HAX1 antibody|HAX1_HUMAN antibody|Hax1a antibody|HCLS1 and PKD2 associated protein antibody|HCLS1 associated protein antibody|HCLS1 associated protein X 1 antibody|HCLS1-associated protein X-1 antibody|HCLSBP1 antibody|HS 1 associated protein X 1 antibody|HS 1 binding protein antibody|HS1 associating protein X 1 antibody|HS1 binding protein 1 antibody|HS1 binding protein antibody|HS1-associating protein X-1 antibody|HS1-binding protein 1 antibody|HS1BP1 antibody|HSP1BP-1 antibody|OTTHUMP00000034190 antibody|SCN3 antibody|Anti-HAX1 antibody (ab137613)

SCBT cat No: sc-166845|sc-34273|sc-28268|sc-16636|sc-16637|

Name

Rabbit polyclonal HAX1 antibody

Catalogue No.

A5551

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human HAX1

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:10 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 31kDa/Observed: Refer to Figures

Formulation

HAX1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

HAX1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

SCN3 antibody, HS1BP1 antibody, HCLSBP1 antibody

Database links

Human UniProt/Swiss-Prot:O00165

Protein names

SCN3, HS1BP1, HCLSBP1

Protein function

Promotes cell survival. Potentiates GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. May regulate intracellular calcium pools.

Protein tissue specificity

Ubiquitous. Up-regulated in oral cancers.

Protein sequence and domain

Belongs to the HAX1 family.

Protein post-translational modifications

Proteolytically cleaved by caspase-3 during apoptosis.

Protein cellular localization

Mitochondrion. Endoplasmic reticulum. Nucleus membrane. Cytoplasmic vesicle . Sarcoplasmic reticulum .

Background

The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene.

Note

AntibodyPlus can customize HAX1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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