Rabbit polyclonal HELLS antibody (A5831)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF,IP,CHIP
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal HELLS antibody (A5831)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF,IP,CHIP

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200 IP 1:50 – 1:200 ChIP 1:20 – 1:100

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal HELLS antibody.

Alternative names:

Check alternative names for the antibody

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LSH antibody, PASG antibody, SMARCA6 antibody, Nbla10143 antibody
FLJ10339 antibody||Anti-SMARCA6 antibody (ab3851)

SCBT cat No: sc-136459|sc-365815|sc-365814|sc-28202|sc-46665|sc-11841|

Name

Rabbit polyclonal HELLS antibody

Catalogue No.

A5831

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human HELLS

Host

Rabbit

Applications

WB, IHC, IF, IP, CHIP

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200
IP 1:50 – 1:200
ChIP 1:20 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 97kDa/Observed: Refer to Figures

Formulation

HELLS antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

HELLS antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

LSH antibody, PASG antibody, SMARCA6 antibody, Nbla10143 antibody

Database links

Human UniProt/Swiss-Prot:Q9NRZ9

Protein names

LSH, PASG, SMARCA6, Nbla10143

Protein function

Plays an essential role in normal development and survival. Involved in regulation of the expansion or survival of lymphoid cells. Required for de novo or maintenance DNA methylation. May control silencing of the imprinted CDKN1C gene through DNA methylation. May play a role in formation and organization of heterochromatin, implying a functional role in the regulation of transcription and mitosis (By similarity).

Protein tissue specificity

Highly expressed in proliferative tissues such as adult thymus and testis, and expressed at lower levels in uterus, small intestine, colon, and peripheral blood mononuclear cells. Also expressed in neoplastic cell lines including those derived from myeloid and lymphoid leukemias.

Protein sequence and domain

Belongs to the SNF2/RAD54 helicase family.; Contains 1 helicase ATP-binding domain.; Contains 1 helicase C-terminal domain.

Protein cellular localization

Nucleus . Note: Closely associated with pericentric heterochromatin.

Background

This gene encodes a lymphoid-specific helicase. Other helicases function in processes involving DNA strand separation, including replication, repair, recombination, and transcription. This protein is thought to be involved with cellular proliferation and may play a role in leukemogenesis. Alternatively spliced transcript variants encoding different isoforms have been identified.

Note

AntibodyPlus can customize HELLS antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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