Rabbit polyclonal HERC3 antibody (A8567)

$69.00$259.00

Reactivity: Human,Mouse
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal HERC3 antibody (A8567)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:100

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

HECT and RLD domain containing E3 ubiquitin protein ligase 3 antibody|HECT domain and RCC1 like domain containing protein 3 antibody|Hect domain and RLD 3 antibody|HERC 3 antibody|KIAA0032 antibody|Probable E3 ubiquitin protein ligase HERC3 antibody|Anti-HERC3 antibody (ab100908)

SCBT cat No: sc-100720|

Name

Rabbit polyclonal HERC3 antibody

Catalogue No.

A8567

Reactivity

Human, Mouse

Immunogen

Recombinant protein of human HERC3

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 117kDa/Observed: Refer to figures

Formulation

HERC3 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

HERC3 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Database links

Human UniProt/Swiss-Prot:Q15034

Protein function

E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

Protein sequence and domain

Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain.; Contains 7 RCC1 repeats.

Protein post-translational modifications

Ubiquitinated; which promotes degradation by the proteasome.

Protein cellular localization

Cytoplasm. Cytoplasmic vesicle. Note: Also found in vesicular-like structures.

Background

This gene encodes a member the HERC ubiquitin ligase family. The encoded protein is located in the cytosol and binds ubiquitin via a HECT domain. Mutations in this gene have been associated with colorectal and gastric carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Note

AntibodyPlus can customize HERC3 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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