Rabbit polyclonal HFE antibody (A1310)

$69.00$259.00

Reactivity: Human,Mouse
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal HFE antibody (A1310)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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HH antibody, HFE1 antibody, HLA-H antibody, MVCD7 antibody, TFQTL2 antibody, MGC103790 antibody,dJ221C16.10.1 antibody
dJ221C16.10.1 antibody|Hemochromatosis antibody|Hemochromatosis protein antibody|Hereditary hemochromatosis protein antibody|Hereditary hemochromatosis protein HLA H antibody|HFE 1 antibody|HFE antibody|HFE_HUMAN antibody|HFE1 antibody|HH antibody|High Fe antibody|HLA H antibody|HLA-H antibody|HLAH antibody|MGC:150812 antibody|MGC10379 antibody|MGC103790 antibody|MHC class I like protein HFE antibody|MVCD7 antibody|TFQTL2 antibody|Anti-HFE antibody (ab176123)

SCBT cat No: sc-18810|

Name

Rabbit polyclonal HFE antibody

Catalogue No.

A1310

Reactivity

Human, Mouse

Immunogen

Recombinant protein of human HFE

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 40kDa/Observed: Refer to Figures

Formulation

HFE antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

HFE antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

HH antibody, HFE1 antibody, HLA-H antibody, MVCD7 antibody, TFQTL2 antibody, MGC103790 antibody,dJ221C16.10.1 antibody

Database links

Human UniProt/Swiss-Prot:Q30201

Protein names

HH, HFE1, HLA-H, MVCD7, TFQTL2, MGC103790,dJ221C16.10.1

Protein function

Binds to transferrin receptor (TFR) and reduces its affinity for iron-loaded transferrin.

Protein tissue specificity

Expressed in all tissues tested except brain.

Protein sequence and domain

Belongs to the MHC class I family.; Contains 1 Ig-like C1-type (immunoglobulin-like) domain.

Protein cellular localization

Cell membrane ; Single-pass type I membrane protein .

Background

The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]

Research area

All research areas>Lymphocyte Signaling>HFE
(View all antibody categories related to Lymphocyte Signaling)

Note

AntibodyPlus can customize HFE antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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