Rabbit polyclonal HK1 antibody (A1054)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal HK1 antibody (A1054)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal HK1 antibody.

Alternative names:

Check alternative names for the antibody

Expand

HK1 antibody,HK1-ta antibody,HK1-tb antibody,HK1-tc antibody,HKI antibody,HXK1 antibody
Brain form hexokinase antibody|Hexokinase 1 antibody|Hexokinase type I antibody|HK I antibody|HK1 ta antibody|HK1 tb antibody|HK1 tc antibody|HKI antibody|HXK1 antibody|Anti-pan-Hexokinase antibody [4D7] (ab58979)

SCBT cat No: sc-80978|sc-390517|sc-271865|sc-6518|sc-46695|sc-28885|

Name

Rabbit polyclonal HK1 antibody

Catalogue No.

A1054

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human HK1

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 102kDa/Observed: Refer to Figures

Formulation

HK1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

HK1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

HK1 antibody,HK1-ta antibody,HK1-tb antibody,HK1-tc antibody,HKI antibody,HXK1 antibody

Database links

Human UniProt/Swiss-Prot:P19367

Protein names

HK1,HK1-ta,HK1-tb,HK1-tc,HKI,HXK1

Protein tissue specificity

Isoform 2 is erythrocyte specific. Isoform 3 and isoform 4 are testis-specific.

Protein sequence and domain

The N- and C-terminal halves of this hexokinase show extensive sequence similarity to each other. The catalytic activity is associated with the C-terminus while regulatory function is associated with the N-terminus. Each domain can bind a single glucose and Gluc-6-P molecule.Belongs to the hexokinase family.; Contains 2 hexokinase domains.

Protein cellular localization

Mitochondrion outer membrane. Note: Its hydrophobic N-terminal sequence may be involved in membrane binding.

Background

Hexokinase catalyzes the conversion of glucose to glucose-6-phosphate, the first step in glycolysis. Four distinct mammalian hexokinase isoforms, designated as hexokinase I, II, III, and IV (glucokinase), have been identified. Hexokinases I, II, and III are associated with the outer mitochondrial membrane and are critical for maintaining an elevated rate of aerobic glycolysis in cancer cells (Warburg Effect) (1) in order to compensate for the increased energy demands associated with rapid cell growth and proliferation (2,3).

Research area

All research areas>Kinases and Phosphatases>HXK
(View all antibody categories related to Kinases and Phosphatases)

Note

AntibodyPlus can customize HK1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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