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Rabbit polyclonal HK1 antibody (A1054)
$69.00–$259.00
Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.
Rabbit polyclonal HK1 antibody (A1054)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC,IF
Recommended dilution:
WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200
Recommended protocols: check protocols
Image descriptions:
Click or hover above images to see image description for Rabbit polyclonal HK1 antibody.
Alternative names:
Check alternative names for the antibody
ExpandHK1 antibody,HK1-ta antibody,HK1-tb antibody,HK1-tc antibody,HKI antibody,HXK1 antibody
Brain form hexokinase antibody|Hexokinase 1 antibody|Hexokinase type I antibody|HK I antibody|HK1 ta antibody|HK1 tb antibody|HK1 tc antibody|HKI antibody|HXK1 antibody|Anti-pan-Hexokinase antibody [4D7] (ab58979)
SCBT cat No: sc-80978|sc-390517|sc-271865|sc-6518|sc-46695|sc-28885|
Name | Rabbit polyclonal HK1 antibody |
---|---|
Catalogue No. | A1054 |
Reactivity | Human, Mouse, Rat |
Immunogen | Recombinant protein of human HK1 |
Host | Rabbit |
Applications | WB, IHC, IF |
Recommended dilution | WB 1:500 – 1:2000 |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Molecular weight | Predicted: 102kDa/Observed: Refer to Figures |
Formulation | HK1 antibody was tube-contained. |
Purification | HK1 antibody was purified using affinity purification. |
Storage | Store at -20 Celsius degree. Avoid freeze / thaw cycles. |
Alternative antibody names | HK1 antibody,HK1-ta antibody,HK1-tb antibody,HK1-tc antibody,HKI antibody,HXK1 antibody |
Database links | Human UniProt/Swiss-Prot:P19367 |
Protein names | HK1,HK1-ta,HK1-tb,HK1-tc,HKI,HXK1 |
Protein tissue specificity | Isoform 2 is erythrocyte specific. Isoform 3 and isoform 4 are testis-specific. |
Protein sequence and domain | The N- and C-terminal halves of this hexokinase show extensive sequence similarity to each other. The catalytic activity is associated with the C-terminus while regulatory function is associated with the N-terminus. Each domain can bind a single glucose and Gluc-6-P molecule.Belongs to the hexokinase family.; Contains 2 hexokinase domains. |
Protein cellular localization | Mitochondrion outer membrane. Note: Its hydrophobic N-terminal sequence may be involved in membrane binding. |
Background | Hexokinase catalyzes the conversion of glucose to glucose-6-phosphate, the first step in glycolysis. Four distinct mammalian hexokinase isoforms, designated as hexokinase I, II, III, and IV (glucokinase), have been identified. Hexokinases I, II, and III are associated with the outer mitochondrial membrane and are critical for maintaining an elevated rate of aerobic glycolysis in cancer cells (Warburg Effect) (1) in order to compensate for the increased energy demands associated with rapid cell growth and proliferation (2,3). |
Research area | All research areas>Kinases and Phosphatases>HXK |
Note | AntibodyPlus can customize HK1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation. |
Product type | Primary antibody |
Supplier | ABclonal Inc. |
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