Rabbit polyclonal HK2 antibody (A0994)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal HK2 antibody (A0994)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

HK2 antibody,DKFZp686M1669 antibody,HKII antibody,HXK2 antibody
DKFZp686M1669 antibody|Hexokinase 2 antibody|Hexokinase 2 muscle antibody|Hexokinase type II antibody|Hexokinase-2 antibody|HK 2 antibody|HK II antibody|HK2 antibody|HKII antibody|HxK 2 antibody|HxK2 antibody|HXK2_HUMAN antibody|Muscle form hexokinase antibody|Anti-Hexokinase II antibody [3D3] (ab104836)

SCBT cat No: sc-130358|sc-374091|sc-6521|sc-28889|sc-6522|

Name

Rabbit polyclonal HK2 antibody

Catalogue No.

A0994

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human HK2

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 102kDa/Observed: Refer to Figures

Formulation

HK2 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

HK2 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

HK2 antibody,DKFZp686M1669 antibody,HKII antibody,HXK2 antibody

Database links

Human UniProt/Swiss-Prot:P52789

Protein names

HK2,DKFZp686M1669,HKII,HXK2

Protein tissue specificity

Predominant hexokinase isozyme expressed in insulin-responsive tissues such as skeletal muscle.

Protein sequence and domain

The N- and C-terminal halves of this hexokinase show extensive sequence similarity to each other. The catalytic activity is associated with the C-terminus while regulatory function is associated with the N-terminus. Each domain can bind a single glucose and Gluc-6-P molecule.Belongs to the hexokinase family.; Contains 2 hexokinase domains.

Protein cellular localization

Mitochondrion outer membrane . Note: Its hydrophobic N-terminal sequence may be involved in membrane binding.

Background

Hexokinase catalyzes the conversion of glucose to glucose-6-phosphate, the first step in glycolysis. Four distinct mammalian hexokinase isoforms, designated as hexokinase I, II, III, and IV (glucokinase), have been identified. Hexokinases I, II, and III are associated with the outer mitochondrial membrane and are critical for maintaining an elevated rate of aerobic glycolysis in cancer cells (Warburg Effect) (1) in order to compensate for the increased energy demands associated with rapid cell growth and proliferation (2,3).

Research area

All research areas>Kinases and Phosphatases>HXK
(View all antibody categories related to Kinases and Phosphatases)

Note

AntibodyPlus can customize HK2 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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