Rabbit polyclonal HLTF antibody (A8353)

$69.00$259.00

Reactivity: Human
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal HLTF antibody (A8353)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

ZBU1 antibody, HLTF1 antibody, RNF80 antibody, HIP116 antibody, SNF2L3 antibody, HIP116A antibody, SMARCA3 antibody
DNA-binding protein/plasminogen activator inhibitor 1 regulator antibody|ZBU 1 antibody|ZBU1 antibody|Anti-HLTF antibody – ChIP Grade (ab17984)

SCBT cat No: sc-398357|sc-366563|

Name

Rabbit polyclonal HLTF antibody

Catalogue No.

A8353

Reactivity

Human

Immunogen

Recombinant protein of human HLTF

Host

Rabbit

Applications

WB

Recommended dilution

WB 1:500 – 1:2000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 114kDa/Observed: Refer to figures

Formulation

HLTF antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

HLTF antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

ZBU1 antibody, HLTF1 antibody, RNF80 antibody, HIP116 antibody, SNF2L3 antibody, HIP116A antibody, SMARCA3 antibody

Database links

Human UniProt/Swiss-Prot:Q14527

Protein names

ZBU1, HLTF1, RNF80, HIP116, SNF2L3, HIP116A, SMARCA3

Protein function

Has both helicase and E3 ubiquitin ligase activities. Possesses intrinsic ATP-dependent nucleosome-remodeling activity; This activity may be required for transcriptional activation or repression of specific target promoters (By similarity). These may include the SERPINE1 and HIV-1 promoters and the SV40 enhancer, to which this protein can bind directly. Plays a role in error-free postreplication repair (PRR) of damaged DNA and maintains genomic stability through acting as a ubiquitin ligase for ‘Lys-63’-linked polyubiquitination of chromatin-bound PCNA.

Protein tissue specificity

Expressed in brain, heart, kidney, liver, lung, pancreas, placenta and skeletal muscle.

Protein sequence and domain

Belongs to the SNF2/RAD54 helicase family. RAD16 subfamily.; Contains 1 helicase ATP-binding domain.; Contains 1 helicase C-terminal domain.; Contains 1 RING-type zinc finger.

Protein cellular localization

Cytoplasm . Nucleus . Nucleus, nucleolus . Nucleus, nucleoplasm . Note: Nuclear localization is stimulated by progesterone.

Background

This gene encodes a member of the SWI/SNF family. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein contains a RING finger DNA binding motif. Two transcript variants encoding the same protein have been found for this gene. However, use of an alternative translation start site produces an isoform that is truncated at the N-terminus compared to the full-length protein.

Note

AntibodyPlus can customize HLTF antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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