Rabbit polyclonal HMBS antibody (A1777)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal HMBS antibody (A1777)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

UPS antibody, PBGD antibody, PORC antibody, PBG-D antibody
HEM3_HUMAN antibody|HMBS antibody|Hydroxymethylbilane synthase antibody|PBG D antibody|PBG-D antibody|PBGD antibody|PORC antibody|Porphobilinogen deaminase antibody|porphyria, acute; Chester type antibody|Pre uroporphyrinogen synthase antibody|Pre-uroporphyrinogen synthase antibody|UPS antibody|Uroporphyrinogen I synthase antibody|Uroporphyrinogen I synthetase antibody|Anti-HMBS antibody [EPR8105] (ab129092)

SCBT cat No: sc-46618|sc-166742|sc-166788|sc-46619|sc-166743|sc-166842|sc-67037|

Name

Rabbit polyclonal HMBS antibody

Catalogue No.

A1777

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human HMBS

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 39kDa/Observed: Refer to Figures

Formulation

HMBS antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

HMBS antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

UPS antibody, PBGD antibody, PORC antibody, PBG-D antibody

Database links

Human UniProt/Swiss-Prot:P08397

Protein names

UPS, PBGD, PORC, PBG-D

Protein function

Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

Protein tissue specificity

Isoform 1 is ubiquitously expressed. Isoform 2 is found only in erythroid cells.

Protein sequence and domain

Belongs to the HMBS family.

Protein cellular localization

Cytoplasm .

Background

This gene encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Note

AntibodyPlus can customize HMBS antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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