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Rabbit polyclonal HMGCL antibody (A8052)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC
WB 1:500 – 1:2000 IHC 1:50 – 1:200
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal HMGCL antibody.
Check alternative names for the antibodyExpand
3 hydroxy 3 methylglutaryl CoA lyase antibody|3 hydroxy 3 methylglutaryl Coenzyme A lyase antibody|3 hydroxymethyl 3 methylglutaryl Coenzyme A lyase (hydroxymethylglutaricaciduria) antibody|3 hydroxymethyl 3 methylglutaryl Coenzyme A lyase antibody|3-hydroxy-3-methylglutarate-CoA lyase antibody|HL antibody|HMG CoA lyase antibody|HMG CoA Lyase Deficiency antibody|HMG-CoA lyase antibody|HMGCL antibody|HMGCL_HUMAN antibody|Hydroxymethylglutaricaciduria antibody|Hydroxymethylglutaryl CoA lyase antibody|Hydroxymethylglutaryl CoA lyase mitochondrial antibody|Hydroxymethylglutaryl-CoA lyase antibody|Mitochondrial 3 hydroxy 3 methylglutaryl CoA lyase antibody|mitochondrial antibody|MS725 antibody|OTTHUMP00000044830 antibody|Anti-HMGCL antibody [EPR15550] – N-terminal (ab187648)
SCBT cat No: sc-100548|sc-101973|sc-133661|
Rabbit polyclonal HMGCL antibody
|Catalogue No.|| |
Recombinant protein of human HMGCL
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 34kDa/Observed: Refer to figures
HMGCL antibody was tube-contained.
HMGCL antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
|Database links|| |
|Protein names|| |
|Protein function|| |
Key enzyme in ketogenesis (ketone body formation). Terminal step in leucine catabolism. Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism.
|Protein tissue specificity|| |
Highest expression in liver. Expressed in pancreas, kidney, intestine, testis, fibroblasts and lymphoblasts. Very low expression in brain and skeletal muscle. The relative expression of isoform 2 (at mRNA level) is highest in heart (30%), skeletal muscle (22%), and brain (14%).
|Protein sequence and domain|| |
Belongs to the HMG-CoA lyase family.
|Protein cellular localization|| |
Mitochondrion matrix. Peroxisome. Note: Unprocessed form is peroxisomal.
The protein encoded by this gene belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a key role in ketone body formation. Mutations in this gene are associated with HMG-CoA lyase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
AntibodyPlus can customize HMGCL antibody according to your requirement, including bulk product size,etc. Please contact firstname.lastname@example.org. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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