Rabbit polyclonal HMGN1 antibody (A6155)

$69.00$259.00

Reactivity: Human,Mouse
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal HMGN1 antibody (A6155)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:100

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal HMGN1 antibody.

Alternative names:

Check alternative names for the antibody

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HMG14 antibody
FLJ27265 antibody|FLJ31471 antibody|High mobility group (nonhistone chromosomal) protein 14 antibody|High mobility group nucleosome binding 1 antibody|High mobility group nucleosome binding domain 1 antibody|High mobility group nucleosome binding domain containing protein 1 antibody|High mobility group nucleosome-binding domain-containing protein 1 antibody|High mobility group protein 14 antibody|HMG 14 antibody|HMG14 antibody|HMGN 1 antibody|HMGN1 antibody|HMGN1_HUMAN antibody|MGC104230 antibody|MGC117425 antibody|Non-histone chromosomal protein HMG-14 antibody|Nonhistone chromosomal protein HMG 14 antibody|Nonhistone chromosomal protein HMG14 antibody|Phospho anti-HMG14 (S20 + S24) antibody (ab115307)

SCBT cat No: sc-19074|sc-19073|sc-101067|

Name

Rabbit polyclonal HMGN1 antibody

Catalogue No.

A6155

Reactivity

Human, Mouse

Immunogen

A synthetic peptide of human HMGN1

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 11kDa/Observed: Refer to figures

Formulation

HMGN1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

HMGN1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

HMG14 antibody

Database links

Human UniProt/Swiss-Prot:P05114

Protein names

HMG14

Protein function

Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation. Inhibits the phosphorylation of nucleosomal histones H3 and H2A by RPS6KA5/MSK1 and RPS6KA3/RSK2 (By similarity).

Protein sequence and domain

Belongs to the HMGN family.

Protein post-translational modifications

Phosphorylation on Ser-21 and Ser-25 weakens binding to nucleosomes and increases the rate of H3 phosphorylation (By similarity). Phosphorylation favors cytoplasmic localization.

Protein cellular localization

Nucleus. Cytoplasm. Note: Cytoplasmic enrichment upon phosphorylation. The RNA edited version localizes to the nucleus.

Background

The protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein, HMG17, the encoded protein may help maintain an open chromatin configuration around transcribable genes.

Research area

All research areas>Transcription Regulators>HMG
(View all antibody categories related to Transcription Regulators)

Note

AntibodyPlus can customize HMGN1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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