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Rabbit polyclonal HNMT antibody (A2520)
$69.00–$259.00
Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.
Rabbit polyclonal HNMT antibody (A2520)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC,IF
Recommended dilution:
WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200
Recommended protocols: check protocols
Image descriptions:
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Alternative names:
Check alternative names for the antibody
ExpandHMT antibody, HNMT-S1 antibody, HNMT-S2 antibody
EC 2.1.1.8 antibody|Histamine N methyltransferase antibody|Histamine N-methyltransferase antibody|HMT antibody|HNMT antibody|HNMT S1 antibody|HNMT S2 antibody|HNMT_HUMAN antibody|Anti-HNMT antibody (ab196611)
SCBT cat No: sc-374306|
Name | Rabbit polyclonal HNMT antibody |
---|---|
Catalogue No. | A2520 |
Reactivity | Human, Mouse, Rat |
Immunogen | Recombinant protein of human HNMT |
Host | Rabbit |
Applications | WB, IHC, IF |
Recommended dilution | WB 1:500 – 1:2000 |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Molecular weight | Predicted: 33kDa/Observed: Refer to Figures |
Formulation | HNMT antibody was tube-contained. |
Purification | HNMT antibody was purified using affinity purification. |
Storage | Store at -20 Celsius degree. Avoid freeze / thaw cycles. |
Alternative antibody names | HMT antibody, HNMT-S1 antibody, HNMT-S2 antibody |
Database links | Human UniProt/Swiss-Prot:P50135 |
Protein names | HMT, HNMT-S1, HNMT-S2 |
Protein function | Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine. |
Protein sequence and domain | Belongs to the class I-like SAM-binding methyltransferase superfamily. HNMT family. |
Protein cellular localization | Cytoplasm . |
Background | In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene. |
Note | AntibodyPlus can customize HNMT antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation. |
Product type | Primary antibody |
Supplier | ABclonal Inc. |
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