Rabbit polyclonal HNMT antibody (A2520)

Rabbit polyclonal HNMT antibody

Human, Mouse, Rat

Rabbit

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Unconjugated

Predicted: 33kDa/Observed: Refer to Figures

HNMT antibody was purified using affinity purification.

HMT antibody, HNMT-S1 antibody, HNMT-S2 antibody

HMT, HNMT-S1, HNMT-S2

Belongs to the class I-like SAM-binding methyltransferase superfamily. HNMT family.

In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.

Primary antibody