Rabbit Polyclonal HNRNPLL antibody (A10360)

$99.00$259.00

Reactivity: Human,Mouse
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit Polyclonal HNRNPLL antibody (A10360)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

SRRF antibody; HNRPLL antibody;
BLOCK24 antibody|Heterogeneous nuclear ribonucleoprotein L like antibody|Heterogeneous nuclear ribonucleoprotein L-like antibody|HNRLL_HUMAN antibody|hnRNPLL antibody|HNRPLL antibody|SRRF antibody|Stromal RNA regulating factor antibody|Stromal RNA-regulating factor antibody|Anti-HNRPLL antibody (ab66775)

SCBT cat No: sc-390699|sc-390455|sc-390611|

Name

Rabbit Polyclonal HNRNPLL antibody

Catalogue No.

A10360

Reactivity

Human, Mouse

Immunogen

Recombinant protein of human HNRNPLL

Host

Rabbit

Applications

WB

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

60kDa

Formulation

HNRNPLL antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

Affinity purification

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

SRRF antibody; HNRPLL antibody;

Protein names

SRRF; HNRPLL;

Protein function

RNA-binding protein that functions as regulator of alternative splicing for multiple target mRNAs, including PTPRC/CD45 and STAT5A. Required for alternative splicing of PTPRC.

Protein tissue specificity

Widely expressed. Detected in bone marrow stroma cells, skeletal muscle, heart, placenta, pancreas, kidney and lung.

Protein sequence and domain

Contains 3 RRM (RNA recognition motif) domains.

Background

HNRNPLL is a master regulator of activation-induced alternative splicing in T cells. In particular, it alters splicing of CD45 (PTPRC; MIM 151460), a tyrosine phosphatase essential for T-cell development and activation (Oberdoerffer et al., 2008

Research area

<a href="http://antibodyplus.com/research-areas/">All research areas</a>><a href="http://antibodyplus.com/Transcription-Regulators/">Transcription Regulators</a>><a href="http://antibodyplus.com/product-tag/hnRNP-A/">hnRNP A</a><br><a href="http://antibodyplus.com/product-tag/Transcription-Regulators/"&gt; (View all antibody categories related to Transcription Regulators)</a>

Note

AntibodyPlus can customize HNRNPLL antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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