Rabbit polyclonal HTR3A antibody (A5647)

$69.00$259.00

Reactivity: Human,Mouse
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal HTR3A antibody (A5647)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal HTR3A antibody.

Alternative names:

Check alternative names for the antibody

Expand

HTR3 antibody, 5HT3R antibody, 5-HT-3 antibody, 5-HT3A antibody, 5-HT3R antibody
5 HT 3 antibody|5 HT3 receptor antibody|5 HT3A antibody|5 HT3A receptor antibody|5 HT3RA antibody|5 hydroxytryptamine (serotonin) receptor 3A antibody|5-HT-3 antibody|5-HT3-A antibody|5-HT3A antibody|5-HT3R antibody|5-hydroxytryptamine receptor 3 antibody|5-hydroxytryptamine receptor 3A antibody|5HT receptor antibody|5HT3 serotonin receptor antibody|5HT3A_HUMAN antibody|5HT3R antibody|HTR3 antibody|Htr3a antibody|Serotonin receptor 3A antibody|Serotonin-gated ion channel receptor 3a antibody|Serotonin-gated ion channel receptor antibody|Anti-5HT3A receptor antibody (ab13897)

SCBT cat No:

Name

Rabbit polyclonal HTR3A antibody

Catalogue No.

A5647

Reactivity

Human, Mouse

Immunogen

Recombinant protein of human HTR3A

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 55kDa/Observed: Refer to Figures

Formulation

HTR3A antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

HTR3A antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

HTR3 antibody, 5HT3R antibody, 5-HT-3 antibody, 5-HT3A antibody, 5-HT3R antibody

Database links

Human UniProt/Swiss-Prot:P46098

Protein names

HTR3, 5HT3R, 5-HT-3, 5-HT3A, 5-HT3R

Protein function

This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel.

Protein tissue specificity

Expressed in cerebral cortex, amygdala, hippocampus, and testis. Detected in monocytes of the spleen and tonsil, in small and large intestine, uterus, prostate, ovary and placenta.

Protein sequence and domain

Belongs to the ligand-gated ion channel (TC 1.A.9) family. 5-hydroxytryptamine receptor (TC 1.A.9.2) subfamily. HTR3A sub-subfamily.

Protein cellular localization

Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.

Background

The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified.

Research area

All research areas>Neurobiology>SR
(View all antibody categories related to Neurobiology)

Note

AntibodyPlus can customize HTR3A antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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