Rabbit polyclonal HYAL1 antibody (A6623)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal HYAL1 antibody (A6623)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

MPS9 antibody, NAT6 antibody, LUCA1 antibody, HYAL-1 antibody
HYAL 1 antibody|Hyal-1 antibody|HYAL1 antibody|HYAL1_HUMAN antibody|Hyaluronidase 1 antibody|Hyaluronidase-1 antibody|Hyaluronoglucosaminidase 1 antibody|Hyaluronoglucosaminidase-1 antibody|Hyaluronoglucosaminidase1 antibody|LUCA 1 antibody|LUCA-1 antibody|LUCA1 antibody|Lung carcinoma protein 1 antibody|MGC45987 antibody|NAT6 antibody|Plasma hyaluronidase antibody|Tumor suppressor LUCA 1 antibody|Anti-HYAL1 antibody (ab85375)

SCBT cat No: sc-101340|sc-101341|sc-514634|sc-99448|

Name

Rabbit polyclonal HYAL1 antibody

Catalogue No.

A6623

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human HYAL1

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 48kDa/Observed: Refer to figures

Formulation

HYAL1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

HYAL1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

MPS9 antibody, NAT6 antibody, LUCA1 antibody, HYAL-1 antibody

Database links

Human UniProt/Swiss-Prot:Q12794

Protein names

MPS9, NAT6, LUCA1, HYAL-1

Protein function

May have a role in promoting tumor progression. May block the TGFB1-enhanced cell growth.

Protein tissue specificity

Highly expressed in the liver, kidney and heart. Weakly expressed in lung, placenta and skeletal muscle. No expression detected in adult brain. Isoform 1 is expressed only in bladder and prostate cancer cells, G2/G3 bladder tumor tissues and lymph node specimens showing tumor invasive tumors cells. Isoform 3, isoform 4, isoform 5 and isoform 6 are expressed in normal bladder and bladder tumor tissues.

Protein sequence and domain

Belongs to the glycosyl hydrolase 56 family.; Contains 1 EGF-like domain.

Protein cellular localization

Secreted . Lysosome .

Background

This gene encodes a lysosomal hyaluronidase. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. This enzyme is active at an acidic pH and is the major hyaluronidase in plasma. Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. Multiple transcript variants encoding different isoforms have been found for this gene.

Note

AntibodyPlus can customize HYAL1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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