Rabbit polyclonal ICAM1 antibody (A5597)

$69.00$259.00

Reactivity: Human,Mouse
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal ICAM1 antibody (A5597)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal ICAM1 antibody.

Alternative names:

Check alternative names for the antibody

Expand

BB2 antibody, CD54 antibody, P3.58 antibody
Antigen identified by monoclonal antibody BB2 antibody|BB 2 antibody|BB2 antibody|CD 54 antibody|CD_antigen=CD54 antibody|CD54 antibody|Cell surface glycoprotein P3.58 antibody|Human rhinovirus receptor antibody|ICAM 1 antibody|ICAM-1 antibody|ICAM1 antibody|ICAM1_HUMAN antibody|intercellular adhesion molecule 1 (CD54), human rhinovirus receptor antibody|Intercellular adhesion molecule 1 antibody|Major group rhinovirus receptor antibody|MALA 2 antibody|MALA2 antibody|MyD 10 antibody|MyD10 antibody|P3.58 antibody|Surface antigen of activated B cells, BB2 antibody|Anti-ICAM1 antibody [MEM-111] (ab2213)

SCBT cat No: sc-107|sc-19584|sc-135946|sc-71292|sc-71303|sc-18853|sc-31724|sc-8439|sc-7891|sc-390483|sc-18908|sc-1511|sc-53336|sc-18839|

Name

Rabbit polyclonal ICAM1 antibody

Catalogue No.

A5597

Reactivity

Human, Mouse

Immunogen

Recombinant protein of human ICAM1

Host

Rabbit

Applications

WB

Recommended dilution

WB 1:500 – 1:2000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 57kDa/Observed: Refer to Figures

Formulation

ICAM1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

ICAM1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

BB2 antibody, CD54 antibody, P3.58 antibody

Database links

Human UniProt/Swiss-Prot:P05362

Protein names

BB2, CD54, P3.58

Protein function

ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation.; (Microbial infection) Acts as a receptor for major receptor group rhinovirus A-B capsid proteins . Acts as a receptor for Coxsackievirus A21 capsid proteins . Upon Kaposi’s sarcoma-associated herpesvirus/HHV-8 infection, is degraded by viral E3 ubiquitin ligase MIR2, presumably to prevent lysis of infected cells by cytotoxic T-lymphocytes and NK cell .

Protein sequence and domain

Belongs to the immunoglobulin superfamily. ICAM family.; Contains 5 Ig-like C2-type (immunoglobulin-like) domains.

Protein post-translational modifications

Monoubiquitinated, which is promoted by MARCH9 and leads to endocytosis.

Protein cellular localization

Membrane; Single-pass type I membrane protein.

Background

This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor.

Research area

All research areas>Cell Adhesion Proteins>ICAM
(View all antibody categories related to Cell Adhesion Proteins)

Note

AntibodyPlus can customize ICAM1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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