Rabbit polyclonal IFT57 antibody (A7191)

$69.00$259.00

Reactivity: Human
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit polyclonal IFT57 antibody (A7191)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal IFT57 antibody.

Alternative names:

Check alternative names for the antibody

Expand

HIPPI antibody, MHS4R2 antibody, ESRRBL1 antibody
CDNA FLJ10147 fis clone HEMBA1003369 antibody||Anti-HIPPI antibody (ab5205)

SCBT cat No: sc-390120|sc-130456|sc-21995|

Name

Rabbit polyclonal IFT57 antibody

Catalogue No.

A7191

Reactivity

Human

Immunogen

Recombinant protein of human IFT57

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 49kDa/Observed: Refer to figures

Formulation

IFT57 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

IFT57 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

HIPPI antibody, MHS4R2 antibody, ESRRBL1 antibody

Database links

Human UniProt/Swiss-Prot:Q9NWB7

Protein names

HIPPI, MHS4R2, ESRRBL1

Protein function

Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5′-AAAGACATG-3′ present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.

Protein tissue specificity

Present in many tissues such as brain, thymus, lymph node, lung, liver, skin and kidney (at protein level).

Protein sequence and domain

The pseudo DED region (pDED) meadiates the interaction with HIP1.Belongs to the IFT57 family.

Protein cellular localization

Cytoplasm, cytoskeleton, cilium basal body . Note: Concentrates within the inner segment of cilia.

Note

AntibodyPlus can customize IFT57 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!