Rabbit polyclonal IGF1 antibody (A0303)


Reactivity: Human,Mouse
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit polyclonal IGF1 antibody (A0303)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal IGF1 antibody.

Alternative names:

Check alternative names for the antibody


IGF1 antibody,IGF1A antibody,IGFI antibody
IBP1 antibody|IGF I antibody|IGF IA antibody|IGF IB antibody|IGF-I antibody|Igf1 antibody|IGF1_HUMAN antibody|IGF1A antibody|IGFI antibody|IGFIA antibody|Insulin like growth factor 1 (somatomedin C) antibody|Insulin like growth factor 1 antibody|Insulin like growth factor IA antibody|Insulin like growth factor IB antibody|Insulin-like growth factor I antibody|Mechano growth factor antibody|MGF antibody|OTTHUMP00000195080 antibody|OTTHUMP00000195081 antibody|OTTHUMP00000195082 antibody|OTTHUMP00000195083 antibody|OTTHUMP00000195084 antibody|Somatomedia C antibody|Somatomedin C antibody|Somatomedin-C antibody|Anti-IGF1 antibody (ab9572)

SCBT cat No: sc-7144|sc-1422|sc-9013|sc-74116|


Rabbit polyclonal IGF1 antibody

Catalogue No.



Human, Mouse


A synthetic peptide of human IGF1





Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200







Molecular weight

Predicted: 17kDa/Observed: Refer to Figures


IGF1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.


IGF1 antibody was purified using affinity purification.


Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

IGF1 antibody,IGF1A antibody,IGFI antibody

Database links

Human UniProt/Swiss-Prot:P05019

Protein names


Protein function

The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation . Ca(2+)-dependent exocytosis of IGF1 is required for sensory perception of smell in the olfactory bulb (By similarity). Acts as a ligand for IGF1R. Binds to the alpha subunit of IGF1R, leading to the activation of the intrinsic tyrosine kinase activity which autophosphorylates tyrosine residues in the beta subunit thus initiatiating a cascade of down-stream signaling events leading to activation of the PI3K-AKT/PKB and the Ras-MAPK pathways. Binds to integrins ITGAV:ITGB3 and ITGA6:ITGB4. Its binding to integrins and subsequent ternary complex formation with integrins and IGFR1 are essential for IGF1 signaling. Induces the phosphorylation and activation of IGFR1, MAPK3/ERK1, MAPK1/ERK2 and AKT1 .

Protein sequence and domain

Belongs to the insulin family.

Protein cellular localization

Secreted .


IGF1, also named as IBP1, MGF, IGF-IA and Somatomedin-C, belongs to the insulin family. IGF1 is structurally and functionally related to insulin but have a much higher growth-promoting activity. Altered expression or mutation of IGF1 is associated with several human disorders, including type I diabetes and various forms of cancer. Defects in IGF1 are the cause of insulin-like growth factor I deficiency (IGF1 deficiency) which is an autosomal recessive disorder characterized by growth retardation, sensorineural deafness and mental retardation. The antibody is specific to isoform IGF1A.

Research area

All research areas>Growth Factors and Hormones>IGF
(View all antibody categories related to Growth Factors and Hormones)


AntibodyPlus can customize IGF1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody


ABclonal Inc.


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:

Welcome to AntibodyPlus!