Rabbit polyclonal IHH antibody (A6626)

Rabbit polyclonal IHH antibody

Human, Mouse, Rat

Rabbit

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Unconjugated

Predicted: 45kDa/Observed: Refer to figures

IHH antibody was purified using affinity purification.

BDA1 antibody, HHG2 antibody

BDA1, HHG2

Expressed in embryonic lung, and in adult kidney and liver.

The C-terminal domain displays an autoproteolysis activity and a cholesterol transferase activity. Both activities result in the cleavage of the full-length protein and covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-terminal fragment (N-product). The N-product is the active species in both local and long-range signaling, whereas the C-product has no signaling activity (By similarity).; Cholesterylation is required for N-product targeting to lipid rafts and multimerization.; Palmitoylated. N-palmitoylation is required for N-product multimerization and full activity.

This gene encodes a member of the hedgehog family of secreted signaling molecules. Hedgehog proteins are essential regulators of a variety of developmental processes including growth, patterning and morphogenesis. The encoded protein specifically plays a role in bone growth an differentiation. Mutations in this gene are the cause of brachydactyly type A1 which is characterized by shortening or malformation of the phalanges. Mutations in this gene are also the cause of acrocapitofemoral dysplasia.

AntibodyPlus can customize IHH antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

ABclonal Inc.