No products in the cart.
Rabbit polyclonal IL11RA antibody (A6627)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC
WB 1:500 – 1:2000 IHC 1:50 – 1:200
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal IL11RA antibody.
Check alternative names for the antibodyExpand
CRSDA antibody|hCG_2011440 antibody|I11RA_HUMAN antibody|IL-11 receptor subunit alpha antibody|IL-11R subunit alpha antibody|IL-11R-alpha antibody|IL-11RA antibody|IL11RA antibody|Interleukin 11 receptor alpha antibody|Interleukin 11 receptor alpha chain antibody|Interleukin-11 receptor subunit alpha antibody|MGC2146 antibody|Anti-IL11RA antibody [EPR5446] (ab125015)
SCBT cat No: sc-130920|sc-31419|sc-393057|sc-992|sc-393039|
Rabbit polyclonal IL11RA antibody
|Catalogue No.|| |
Recombinant protein of human IL11RA
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 45kDa/Observed: Refer to figures
IL11RA antibody was tube-contained.
IL11RA antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
|Database links|| |
|Protein names|| |
|Protein function|| |
Receptor for interleukin-11. The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. The IL11/IL11RA/IL6ST complex may be involved in the control of proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells. Essential for the normal development of craniofacial bones and teeth. Restricts suture fusion and tooth number.
|Protein tissue specificity|| |
Expressed in a number of cell lines, including the myelogenous leukemia cell line K-562, the megakaryocytic leukemia cell line M-07e, the erythroleukemia cell line TF-1, and the osteosarcoma cell lines, MG-63 and SaOS-2. Also expressed in normal and malignant prostate epithelial cell lines. Expression levels are increased in prostate carcinoma.
|Protein sequence and domain|| |
Belongs to the type I cytokine receptor family. Type 3 subfamily.; Contains 2 fibronectin type-III domains.; Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
|Protein cellular localization|| |
Membrane; Single-pass type I membrane protein.
Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. This gene encodes the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Multiple alternatively spliced transcript variants have been found for this gene.
AntibodyPlus can customize IL11RA antibody according to your requirement, including bulk product size,etc. Please contact firstname.lastname@example.org. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
There are no reviews for this product yet.
By submitting a review, get following benefits:
1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!
There is no extra validation for this product yet.
Check other extra validated antibodies below: