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Rabbit polyclonal IL17RD antibody (A10031)
$69.00–$259.00
Reactivity: Human,Mouse,Rat
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.
Rabbit polyclonal IL17RD antibody (A10031)
Supplier: ABclonal Inc.
Recommended applications: WB
Recommended dilution:
WB 1:500 – 1:2000
Recommended protocols: check protocols
Image descriptions:
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Alternative names:
Check alternative names for the antibody
ExpandDKFZp434N1928 antibody|FLJ35755 antibody|hSef antibody|I17RD_HUMAN antibody|IL 17 receptor D antibody|IL 17RD antibody|IL-17 receptor D antibody|IL-17RD antibody|IL17 receptor D antibody|il17rd antibody|IL17Rhom antibody|IL17RLM antibody|Interleukin 17 receptor D antibody|Interleukin 17 receptor like protein antibody|Interleukin-17 receptor D antibody|Interleukin-17 receptor-like protein antibody|Interleukin17 receptor D antibody|MGC133309 antibody|SEF antibody|Sef homolog antibody|Anti-IL17RD antibody (ab111553)
SCBT cat No: sc-99940|sc-99941|
| Name | Rabbit polyclonal IL17RD antibody |
|---|---|
| Catalogue No. | A10031 |
| Reactivity | Human, Mouse, Rat |
| Immunogen | Recombinant protein of human IL17RD |
| Host | Rabbit |
| Applications | WB |
| Recommended dilution | WB 1:500 – 1:2000 |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Molecular weight | Predicted: 82kDa/Observed: Refer to figures |
| Formulation | IL17RD antibody was tube-contained. |
| Purification | IL17RD antibody was purified using affinity purification. |
| Storage | Store at -20 Celsius degree. Avoid freeze / thaw cycles. |
| Database links | Human UniProt/Swiss-Prot:Q8NFM7 |
| Protein function | Feedback inhibitor of fibroblast growth factor mediated Ras-MAPK signaling and ERK activation. May inhibit FGF-induced FGFR1 tyrosine phosphorylation. Regulates the nuclear ERK signaling pathway by spatially blocking nuclear translocation of activated ERK without inhibiting cytoplasmic phosphorylation of ERK. Mediates JNK activation and may be involved in apoptosis. Might have a role in the early stages of fate specification of GnRH-secreting neurons (By similarity). |
| Protein tissue specificity | Expressed in umbilical vein endothelial cells and in several highly vascularized tissues such as kidney, colon, skeletal muscle, heart and small intestine. Highly expressed in ductal epithelial cells of salivary glands, seminal vesicles and the collecting tubules of the kidney. Isoform 1 is also highly expressed in both fetal and adult brain, pituitary, tonsils, spleen, adenoids, fetal kidney, liver, testes and ovary. Isoform 1 is also expressed at moderate levels in primary aortic endothelial cells and adrenal medulla, and at low levels in adrenal cortex. Isoform 4 is specifically and highly expressed in pituitary, fetal brain and umbilical vein endothelial cells. |
| Protein sequence and domain | Contains 1 SEFIR domain. |
| Protein cellular localization | Golgi apparatus membrane ; Single-pass type I membrane protein . Cell membrane ; Single-pass type I membrane protein . Note: Predominantly associated with the Golgi apparatus and is partially translocated to the plasma membrane upon stimulation.; Isoform 4: Cytoplasm. |
| Research area | All research areas>Growth Factors and Hormones>IL-17 |
| Note | AntibodyPlus can customize IL17RD antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation. |
| Product type | Primary antibody |
| Supplier | ABclonal Inc. |
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