Rabbit polyclonal IL17RD antibody (A10031)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal IL17RD antibody (A10031)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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DKFZp434N1928 antibody|FLJ35755 antibody|hSef antibody|I17RD_HUMAN antibody|IL 17 receptor D antibody|IL 17RD antibody|IL-17 receptor D antibody|IL-17RD antibody|IL17 receptor D antibody|il17rd antibody|IL17Rhom antibody|IL17RLM antibody|Interleukin 17 receptor D antibody|Interleukin 17 receptor like protein antibody|Interleukin-17 receptor D antibody|Interleukin-17 receptor-like protein antibody|Interleukin17 receptor D antibody|MGC133309 antibody|SEF antibody|Sef homolog antibody|Anti-IL17RD antibody (ab111553)

SCBT cat No: sc-99940|sc-99941|

Name

Rabbit polyclonal IL17RD antibody

Catalogue No.

A10031

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human IL17RD

Host

Rabbit

Applications

WB

Recommended dilution

WB 1:500 – 1:2000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 82kDa/Observed: Refer to figures

Formulation

IL17RD antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

IL17RD antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Database links

Human UniProt/Swiss-Prot:Q8NFM7

Protein function

Feedback inhibitor of fibroblast growth factor mediated Ras-MAPK signaling and ERK activation. May inhibit FGF-induced FGFR1 tyrosine phosphorylation. Regulates the nuclear ERK signaling pathway by spatially blocking nuclear translocation of activated ERK without inhibiting cytoplasmic phosphorylation of ERK. Mediates JNK activation and may be involved in apoptosis. Might have a role in the early stages of fate specification of GnRH-secreting neurons (By similarity).

Protein tissue specificity

Expressed in umbilical vein endothelial cells and in several highly vascularized tissues such as kidney, colon, skeletal muscle, heart and small intestine. Highly expressed in ductal epithelial cells of salivary glands, seminal vesicles and the collecting tubules of the kidney. Isoform 1 is also highly expressed in both fetal and adult brain, pituitary, tonsils, spleen, adenoids, fetal kidney, liver, testes and ovary. Isoform 1 is also expressed at moderate levels in primary aortic endothelial cells and adrenal medulla, and at low levels in adrenal cortex. Isoform 4 is specifically and highly expressed in pituitary, fetal brain and umbilical vein endothelial cells.

Protein sequence and domain

Contains 1 SEFIR domain.

Protein cellular localization

Golgi apparatus membrane ; Single-pass type I membrane protein . Cell membrane ; Single-pass type I membrane protein . Note: Predominantly associated with the Golgi apparatus and is partially translocated to the plasma membrane upon stimulation.; Isoform 4: Cytoplasm.

Research area

All research areas>Growth Factors and Hormones>IL-17
(View all antibody categories related to Growth Factors and Hormones)

Note

AntibodyPlus can customize IL17RD antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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