Rabbit polyclonal IL21 antibody (A7235)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal IL21 antibody (A7235)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal IL21 antibody.

Alternative names:

Check alternative names for the antibody

Expand

Za11 antibody, IL-21 antibody, CVID11 antibody
CVID11 antibody|IL 21 antibody|IL-21 antibody|Il21 antibody|IL21_HUMAN antibody|Interleukin 21 antibody|Interleukin-21 antibody|interleukin-21 isoform antibody|Interleukin21 antibody|OTTHUMP00000164088 antibody|Za11 antibody|Anti-IL21 antibody (ab5978)

SCBT cat No: sc-17651|

Name

Rabbit polyclonal IL21 antibody

Catalogue No.

A7235

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human IL21

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 18kDa/Observed: Refer to figures

Formulation

IL21 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

IL21 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

Za11 antibody, IL-21 antibody, CVID11 antibody

Database links

Human UniProt/Swiss-Prot:Q9HBE4

Protein names

Za11, IL-21, CVID11

Protein function

Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells (By similarity). May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation.

Protein tissue specificity

Expressed in activated CD4-positive T-cells but not in CD8-positive T-cells, B-cells, or monocytes.

Protein sequence and domain

Belongs to the IL-15/IL-21 family.

Protein cellular localization

Secreted .

Background

This gene encodes a member of the common-gamma chain family of cytokines with immunoregulatory activity. The encoded protein plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells. Dysregulation of this gene plays a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Research area

All research areas>Growth Factors and Hormones>IL-21
(View all antibody categories related to Growth Factors and Hormones)

Note

AntibodyPlus can customize IL21 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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