Rabbit polyclonal IL5RA antibody (A8552)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal IL5RA antibody (A8552)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal IL5RA antibody.

Alternative names:

Check alternative names for the antibody

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IL5R antibody, CD125 antibody, CDw125 antibody, HSIL5R3 antibody
CD125 antibody|CD125 antigen antibody|CDw125 antibody|HSIL5R3 antibody|IL-5 receptor subunit alpha antibody|IL-5R subunit alpha antibody|IL-5R-alpha antibody|IL-5RA antibody|IL5R antibody|IL5RA antibody|IL5RA_HUMAN antibody|Interleukin 5 Receptor alpha antibody|Interleukin 5 Receptor alpha chain antibody|Interleukin 5 receptor alpha subunit antibody|Interleukin 5 receptor subunit alpha antibody|Interleukin 5 receptor type 3 antibody|Interleukin-5 receptor subunit alpha antibody|MGC26560 antibody|Anti-IL5RA antibody – C-terminal (ab198808)

SCBT cat No: sc-30009|sc-21904|

Name

Rabbit polyclonal IL5RA antibody

Catalogue No.

A8552

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human IL5RA

Host

Rabbit

Applications

WB

Recommended dilution

WB 1:500 – 1:2000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 48kDa/Observed: Refer to figures

Formulation

IL5RA antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

IL5RA antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

IL5R antibody, CD125 antibody, CDw125 antibody, HSIL5R3 antibody

Database links

Human UniProt/Swiss-Prot:Q01344

Protein names

IL5R, CD125, CDw125, HSIL5R3

Protein function

This is the receptor for interleukin-5. The alpha chain binds to IL5.

Protein tissue specificity

Expressed on eosinophils and basophils.

Protein sequence and domain

The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.; The box 1 motif is required for JAK interaction and/or activation.Belongs to the type I cytokine receptor family. Type 5 subfamily.; Contains 2 fibronectin type-III domains.

Protein cellular localization

Membrane; Single-pass type I membrane protein.

Background

The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported.

Research area

All research areas>Membrane Receptors>IL-3/-5/GM-CSF Receptor Complex
(View all antibody categories related to Membrane Receptors)

Note

AntibodyPlus can customize IL5RA antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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