Rabbit polyclonal IL7 antibody (A1650)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal IL7 antibody (A1650)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

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Alternative names:

Check alternative names for the antibody

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IL-7 antibody
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SCBT cat No:

Name

Rabbit polyclonal IL7 antibody

Catalogue No.

A1650

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human IL7

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 20kDa/Observed: Refer to Figures

Formulation

IL7 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

IL7 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

IL-7 antibody

Database links

Human UniProt/Swiss-Prot:P13232

Protein names

IL-7

Protein function

Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation.

Protein sequence and domain

Belongs to the IL-7/IL-9 family.

Protein cellular localization

Secreted.

Background

IL-7 plays a key role in lymphopoiesis and lymphoid homeostasis (1). Stromal and epithelial cells within the bone marrow and thymus produce IL-7 (1). The primary targets of IL-7 are T cells, B cells, and dendritic cells (1). IL-7 is crucial for T cell development, the importance of which is underscored by the lack of T cells in both mice and humans that are deficient in IL-7/IL-7R signaling (1,2). While IL-7 appears to be required for B cell development in mice, the role of IL-7 in human B cell development is unclear (1,3). In addition to its effects on T cell lymphopoiesis, IL-7 promotes the maintenance and survival of naïve and memory alphabeta T cells, as well as gammadelta T cells (1). The IL-7 receptor is a heterodimer of the common gamma chain, gammac, and the IL-7-specific IL-7Ralpha (1). IL-7 activates PI3K/Akt, Jak1/2, and Stat1, 3, and 5 (1).

Research area

All research areas>Growth Factors and Hormones>IL-7
(View all antibody categories related to Growth Factors and Hormones)

Note

AntibodyPlus can customize IL7 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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