Rabbit Polyclonal IMPDH1 antibody (A9497)

$99.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit Polyclonal IMPDH1 antibody (A9497)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:1000 – 1:2000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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IMDH1_HUMAN antibody|IMP (inosine monophosphate) dehydrogenase 1 antibody|IMP dehydrogenase 1 antibody|IMPD 1 antibody|IMPD antibody|IMPD1 antibody|IMPDH 1 antibody|IMPDH I antibody|IMPDH-I antibody|Impdh1 antibody|Inosine 5′ monophosphate dehydrogenase 1 antibody|Inosine monophosphate dehydrogenase 1 antibody|Inosine-5”-monophosphate dehydrogenase 1 antibody|LCA11 antibody|RP10 antibody|sWSS2608 antibody|Anti-IMPDH1 antibody (ab33039)

SCBT cat No: sc-46146|sc-46147|sc-365171|sc-166551|sc-50510|

Name

Rabbit Polyclonal IMPDH1 antibody

Catalogue No.

A9497

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human IMPDH1

Host

Rabbit

Applications

WB

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

55kDa

Formulation

IMPDH1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

Affinity purification

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Protein function

Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.

Protein tissue specificity

IMP type I is the main species in normal leukocytes and type II predominates over type I in the tumor.

Protein sequence and domain

Belongs to the IMPDH/GMPR family.; Contains 2 CBS domains.

Protein cellular localization

Cytoplasm . Nucleus .

Background

The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]

Note

AntibodyPlus can customize IMPDH1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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