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Rabbit Polyclonal IMPDH1 antibody (A9497)
Supplier: ABclonal Inc.
Recommended applications: WB
WB 1:1000 – 1:2000
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit Polyclonal IMPDH1 antibody.
Check alternative names for the antibodyExpand
IMDH1_HUMAN antibody|IMP (inosine monophosphate) dehydrogenase 1 antibody|IMP dehydrogenase 1 antibody|IMPD 1 antibody|IMPD antibody|IMPD1 antibody|IMPDH 1 antibody|IMPDH I antibody|IMPDH-I antibody|Impdh1 antibody|Inosine 5′ monophosphate dehydrogenase 1 antibody|Inosine monophosphate dehydrogenase 1 antibody|Inosine-5”-monophosphate dehydrogenase 1 antibody|LCA11 antibody|RP10 antibody|sWSS2608 antibody|Anti-IMPDH1 antibody (ab33039)
SCBT cat No: sc-46146|sc-46147|sc-365171|sc-166551|sc-50510|
Rabbit Polyclonal IMPDH1 antibody
|Catalogue No.|| |
Human, Mouse, Rat
Recombinant protein of human IMPDH1
|Recommended dilution|| |
WB 1:1000 – 1:2000
|Molecular weight|| |
IMPDH1 antibody was tube-contained.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Database links|| |
Human UniProt/Swiss-Prot:<a href="http://www.uniprot.org/uniprot/P20839">P20839</a>
|Protein function|| |
Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.
|Protein tissue specificity|| |
IMP type I is the main species in normal leukocytes and type II predominates over type I in the tumor.
|Protein sequence and domain|| |
Belongs to the IMPDH/GMPR family.; Contains 2 CBS domains.
|Protein cellular localization|| |
Cytoplasm . Nucleus .
The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
AntibodyPlus can customize IMPDH1 antibody according to your requirement, including bulk product size,etc. Please contact firstname.lastname@example.org. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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